Re: [ZION] Article in "Science" on genetic diversity

2002-12-21 Thread Marc A. Schindler
In fact, their clusters are in different areas than what we would call "racial".
That is, there are several from different parts of Africa, for instance, as well
as a totally different group for Melanesians (who used to be considered blacks by
LDS until DOM's time).

Jim Cobabe wrote:

> Stephen Beecroft wrote:
> ---
> What?! Is this suggesting the outrageous proposition that
> commonly-defined racial characteristics are  genetically based?
> ---
>
> Spare your outrage, Stephen.
>
> The authors of the study _studiously_ refrain from using the term
> "race".  Instead they characterize unique population groups as
> "clusters".  One cannot help but notice, however, that the "clusters"
> indicated on the map correspond rather remarkably with traditional
> racial demographics, but that's beside the politically-correct point.
>
> One wonders if the authors might have been injured by such strenuous
> bending-over-backwards exertions.  :->
>
> ---
> Mij Ebaboc
>
> //
> ///  ZION LIST CHARTER: Please read it at  ///
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>

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Marc A. Schindler
Spruce Grove, Alberta, Canada -- Gateway to the Boreal Parkland

“Knowledge may give weight, but accomplishments give lustre, and many more people
see than weigh.” – Lord Chesterfield

Note: This communication represents the informal personal views of the author
solely; its contents do not necessarily reflect those of the author’s employer,
nor those of any organization with which the author may be associated.

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RE: [ZION] Article in "Science" on genetic diversity

2002-12-21 Thread Jim Cobabe

Stephen Beecroft wrote:
---
What?! Is this suggesting the outrageous proposition that 
commonly-defined racial characteristics are  genetically based?
---

Spare your outrage, Stephen.

The authors of the study _studiously_ refrain from using the term 
"race".  Instead they characterize unique population groups as 
"clusters".  One cannot help but notice, however, that the "clusters" 
indicated on the map correspond rather remarkably with traditional 
racial demographics, but that's beside the politically-correct point.

One wonders if the authors might have been injured by such strenuous 
bending-over-backwards exertions.  :->

---
Mij Ebaboc

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Re: [ZION] Article in "Science" on genetic diversity

2002-12-20 Thread Marc A. Schindler


Stephen Beecroft wrote:

> -Marc-
> > Within-population differences among individuals account for 93
> > to 95% of genetic variation; differences among major groups
> > constitute only 3 to 5%. Nevertheless, without using prior
> > information about the origins of individuals, we identified
> > six main genetic clusters, five of which correspond to major
> > geographic regions, and subsclusters that often correspond to
> > individual populations.
>
> What?! Is this suggesting the outrageous proposition that
> commonly-defined racial characteristics are  genetically based?
>

That's not what they're suggesting. They say that naturally those people who are
descended from black Africans will have a certain set of features in common. We
recognize that and refer to them as "blacks," which is meant to be a neutral, more
respectful form, I guess.  And those genes for the broadened nose, thick lips and
fuzzy hair are naturally passed on from one generation to the next. What the
article is saying is that the historical background of a population -- and he
gives examples of bizarre places I'd never heard, like a group in NW Pakistan, who
are of Indo-European descent (linguistically and ethnically). But all in all the
genome does not indicate we have a biologically ueful definition of race. If
there's more genetic diversity within, say, a south Asian population, than they
share with other groups.

I know it's not really fair just to post an abstract, because it means I'm giving
you the hay with which to build a straw man. But it's my fault for handing you the
straw (no joke or sarcasm meant).

It may put Tom Murphy in an embarrassing situation, and as some of you know, FAIR
recently put out an article which is linked to in this month's FAIR newsletter.
We've been working hard at finding a conspiracy (yeah, yeah, I know.  "It's
Ironic" as Alannis Morisette might sing), and now that we have smoking guns from
the bugs under the rocks (now there's a mixed metaphor!). The next step is to
address the claims made in his article. Some of this has already done by Scott
Woodward of BYU, who delivered a presentation on the DNA work BYU's doing).
making things just a bit hotter in the "Morque" (www.exmormons.com). I believe Ben
McGuire already has an article up on FAIR's website about DNA research.

In my opinion, unless I'm missing something (genetics is something I know very
little about other than what I've read in Scientific American, say), this pape
(from Science) might put  a big kaibosh on anyone thinking they can prove or
disprove that modern day First Nations descended solely from the Book of Mormon,
which is what Tom Murphy, who admittedly went inactive in 1993, claims in his
review for "American Apocrypha" among other venues.

>
> > General agreement of genetic and predefined populations
> > suggests that self-reported ancestry can facilitate
> > assessments of epidemiological risks
>
> Wow. I guess it is. Who would have believed such a counterintuitive
> idea? (Besides myself and most of the adult population of the western
> world, I mean.)
>
> Stephen
>

What they're saying is that while it may not be true that there's a biological
term for "race," we, as a culture and laypeople, tend to identify themselves with
one race or another. What the full paper shows is that that strictly in terms of
the DNA  samples, you cannot "prove" that one person's black and the other's
Asian, and see that reflected in their DNA. There's a lot of genetic diversity in
Africa -- in fact, more than the rest of the world combined. But because there is
a weak correlation indirectly through the genes that expressed the proces that led
to a "racial" characteristic.  But because we self-identify our race one way or
another when seeing a doctor, we should know that various races have varying
diseases and this will guide the doctor's diagnosis. For or example, if your black
and you feel anemic and run-down, then the doctor needs to check for sickle cell
anaemia, because the gene for that is found widely throughout Africa. While this
mutation gives a significant portion of the population sickle-cell anaemia,
whereas if a Caucasian came in, the doctor should simply do a red blood cell count
(a simple test at a medical lab).

Incidentally, this very racial anomaly, the tendency to get a disease that is not
nearly as common amongst people from other areas from, also provides natural
protection against malaria, which still rampant in most of Africa. So it can go
from, say IF [RACE  = BLACK THEN GOSUB [CHECK FOR MALARIA], But the converse
doesn't hold -- IF [BLOOD TEST FOR SICKLE CELL AMAENIA] = YES. One can't go from
the race alone, even if it's sometimes a useful indicator if the patient tells the
doctor he originally came from West Africa several centuries ago. Another example
is benign prostate infection, which is more common amongst black males than
amongst white males, age-adjusted [at least in the US blacks will get his out of
proportion to t

RE: [ZION] Article in "Science" on genetic diversity

2002-12-20 Thread Stephen Beecroft
-Marc-
> Within-population differences among individuals account for 93
> to 95% of genetic variation; differences among major groups
> constitute only 3 to 5%. Nevertheless, without using prior
> information about the origins of individuals, we identified
> six main genetic clusters, five of which correspond to major
> geographic regions, and subsclusters that often correspond to
> individual populations.

What?! Is this suggesting the outrageous proposition that 
commonly-defined racial characteristics are  genetically based?

> General agreement of genetic and predefined populations
> suggests that self-reported ancestry can facilitate
> assessments of epidemiological risks

Wow. I guess it is. Who would have believed such a counterintuitive 
idea? (Besides myself and most of the adult population of the western 
world, I mean.)

Stephen

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[ZION] Article in "Science" on genetic diversity

2002-12-20 Thread Marc A. Schindler
Coincidence that this appeared in today's issue of "Science," one of the
two best-known and most prestigious general science journals in the
anglophone world (Rosenberg, et. al. Science:298, 20/12/2002:2381). The
article is called "Genetic Structure of Human Populations" by a
multinational team from the US, Russia and France. I have the full
article (as well as the editorial introduction) but here's the abstract:

"We studied human population structure using genotypes at 377 autosomal
microstallite loci in 1056 individuals from 52 populations.
Within-population differences among individuals account for 93 to 95% of
genetic variation; differences among major groups constitute only 3 to
5%. Nevertheless, without using prior information about the origins of
individuals, we identified six main genetic clusters, five of which
correspond to major geographic regions, and subsclusters that often
correspond to individual populations. General agreement of genetic and
predefined populations suggests that self-reported ancestry can
facilitate assessments of epidemiological risks but does not obviate the
need to use genetic information in genetic associations studies."

I'm the first to admit I'm not a geneticist, and much of this article is
over my head. It *seems* to be saying that because there is far more
genetic variation within a given population than there is between
populations, that the use of genetics for the study of human migratory
patterns is only of very weak usefulness. That is, within a given area,
you could often separate populations, but if you tried to compare
populations from one area to populations in another area, there were
rarely any correlations. I could see no correlation between East Asian
and American populations, for instance. But in any case, the difference
between a Colombian sample and a Mayan sample within the greater
American population was greater than differences between the whole
American population and the East Asian populations (which likewise
showed great various between individual groups within the population as
a whole). Any thoughts?

--
Marc A. Schindler
Spruce Grove, Alberta, Canada -- Gateway to the Boreal Parkland

“Knowledge may give weight, but accomplishments give lustre, and many
more people see than weigh.” – Lord Chesterfield

Note: This communication represents the informal personal views of the
author solely; its contents do not necessarily reflect those of the
author’s employer, nor those of any organization with which the author
may be associated.

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