Vince

On Nov 14, 2012, at 9:28 AM, "Ron Daniels" 
<[email protected]<mailto:[email protected]>> wrote:

Hi Stephanie,

Most would suggest arterial lactate is the better measure. Venous lactate can 
be dependent on local perfusion to the sampled limb, whereas arterial lactate 
is analogous to mixed venous oxygen saturation: it's a more appropriate 
surrogate measure of global perfusion.

Pragmatically, if a venous lactate is normal we can be reassured that arterial 
lactate will also be normal. If venous is high, however, it's worth checking 
arterial to rule out regional perfusion abnormalities.

Capillary lactate has also been validated...

Hope this helps

Kind regards

Ron

Dr Ron Daniels
Chair: UK Sepsis Trust
CEO: Global Sepsis Alliance

Sent on the move from my iPhone, excuse brevity!

On 9 Nov 2012, at 16:15, "Shawver, Stephanie" 
<[email protected]<mailto:[email protected]>> wrote:

Colleagues,

Our facility has recently implemented point of care arterial lactate testing as 
an extension of point of care ABG’s. However, all of our sepsis protocols are 
built around the assessment of venous lactate. We are starting to see 
practitioners rely on the arterial lactate rather than the venous lactate and / 
or reassess an elevated arterial lactate with a venous lactate or vice versa. 
It is a concern of mine that if a practitioner sees a normal arterial lactate 
and doesn’t assess the venous lactate as well – it could be missed that the 
venous lactate is elevated (as I understand it, in sepsis the venous lactate 
will be elevated before the arterial lactate becomes elevated). We have had a 
couple cases where the practitioner did not activate the sepsis protocols based 
on a normal arterial lactate, only to find out later the venous lactate was 
elevated and EGDT was delayed.

I have looked into the research and cannot find much about the use of arterial 
lactates in sepsis & all the SSC / EGDT studies focus on the use of venous 
lactate levels. Have any of you ran into this in your sepsis programs and if 
so, how did you address it? And if anyone out there can point me to research 
about arterial vs. venous lactate in sepsis? Any thoughts/feedback/suggestions 
are welcome! Thank you!


Stephanie Shawver BSN, RN
SLMV Sepsis  and Stroke Coordinator
St. Luke's Magic Valley
801 Pole Line Road West  | Twin Falls, ID 83301
Office: (208) 814.4030   |  Email: 
[email protected]<mailto:[email protected]>
 Suspect stroke? Think FAST!
Facial droop, Arm drift, Speech impairment, Time is brain - this is an 
emergency!






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