My understanding is that the GNYHA protocol listed ³empiric fluid loading²
as a choice.   Not sure if that was a protocol.   In addition, my
understanding is that almost 50% of the patients in the initiative had no
recorded method for fluid resuscitation.  Is that correct?

Mitchell Levy


On 5/1/13 3:01 PM, "Mary Daly" <[email protected]> wrote:

> I am surprised that the Œnon-inferiority study¹ referenced here would lead to
> treatment protocols with endpoints that were not endorsed by the Surviving
> Sepsis Campaign. 
> Among the flaws in that study was the arbitrary choice of a Œ10% reduction in
> lactate levels¹. 
> In addition to the fact that this per cent reduction was arbitrary, I think
> that we can all agree that there is quite a difference in a 10% reduction in a
> lactate of 3.9 and a 10% reduction in a lactate of lactate of 8.9. 
>  
> Although the new SSC guidelines include targets for serum lactate
> reduction(begrudgingly to satisfy NQF - IMHO), the goal of the reduction is
> not  by some arbitrary number - but normalized.
>  
> $0.02
> Thanks, 
>  
> Mary Ann Daly, RN BSN CCRN DC
> Regional Clinical Initiative Lead-Sepsis and ICU Liberation (ABCDE)
> Gordon and Betty Moore Foundation Grant
> Sutter Health Sacramento Sierra Region
> E-mail: [email protected] <mailto:[email protected]>
> Blackberry: 916.200.5604   Office: 916.614.6370
>  You never change things by fighting the existing reality. To change
> something, build a new model that makes the existing model obsolete. R.
> Buckminster Fuller
>  
>  
> 
> From: [email protected]
> [mailto:[email protected]] On Behalf Of Ram Parekh
> Sent: Tuesday, April 30, 2013 1:50 PM
> To: Vipul Kella
> Cc: [email protected]
> Subject: Re: [Sepsis Groups] Noninvasive EGDT
>  
> We have at our hospital and at most of the GNYHA hospitals in the New York
> area. 
> 
> This protocol is based on the non-inferiority study of lactate clearance by
> Jones/Shapiro and was implemented with our current Stop Sepsis collaborative
> which has given ED providers the option of utilizing the 'invasive' or
> 'non-invasive protocol' as EGDT options. Thus, the protocol was simultaneously
> implemented in over 50 hospitals at the same time.
> 
> On Mon, Apr 29, 2013 at 9:57 AM, Vipul Kella <[email protected]> wrote:
> 
> Has anyone implemented the noninvasive EGDT protocol at their hospital?  What
> was your experience?
>  

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