For "big" cases I use plasmalyte as my crystalloid  but switch to albumin early 
if I need it.

Sean Funston
Sent from my iPhone

On Jan 28, 2014, at 11:51 AM, "Kramer, George C." 
<[email protected]<mailto:[email protected]>> wrote:

Donna,

A perspective of a physiologist (with an attitude) :)

One to three is the classic ratio and probably good to use for equivalent 
volume expansion of colloid to crystalloid. But crystalloid expansion is quite 
transient and colloids are more sustained.  This is both good and bad depending 
on concerns about volume overload.

I would say that for clinical use 6% albumin and most starches are similar as 
to volume expansion.

I believe our clinicians use LR first and only go to albumin when LR is not 
effective and they don't use any fixed rules.

Also, I believe they prefer LR over NS due to hypercholremic acidosis with 
large volume loads.  I would say that plasmalyte is best crystalloid, but I 
don't see that it is used here much.

At our institution, in ICU and OR it is almost always albumin as the colloids 
and ratios of 1/2 or 1/3 are typically used.  I think there is strong evidence 
developing about the dangers and limitations of starches due to renal 
complications.

I have cc'ed our top docs and they may weigh in.

George,

George Kramer, PhD
Resuscitation Research Lab
Dept. of Anesthesiology
UTMB, Galveston
409-939-3040



From: <Hixson>, Donna 
<[email protected]<mailto:[email protected]>>
Date: Tuesday, January 28, 2014 11:00 AM
To: 
"'[email protected]<mailto:'[email protected]>'"
 
<[email protected]<mailto:[email protected]>>
Subject: [Sepsis Groups] Albumin & Hetastarches

Is there a new conversion list for the hetastarch and albumin fluid amounts?  
Is it safe to say since the colloids are increased by 1/3 the other fluids 
should follow?



<image003.jpg>
With Regards,
Donna Hixson R.N.
Research Outcomes Nurse
Vascular Registry
[email protected]<mailto:[email protected]>
Office (727) 462-7615
Fax (727) 462-3638   MS 73


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