Good morning!

Does anyone have any info regarding IV push antibiotics for first dose 
antibiotic dosing in the ED. We are challanged by some of our payers quality 
"pay for performance" programs in PA to start and COMPLETE first dose 
antibiotics within 3 hours of arrival. Our health system has some fairly 
conservative infusion timing guidelines for nursing  - any ideas or resources 
are appreciated! 

William Jenkins, MD
Excela Health
Emergency Medicine
Pennsylvania

 

________________________________________
From: [email protected] 
[[email protected]] on behalf of Kramer, George C. 
[[email protected]]
Sent: Thursday, February 13, 2014 9:02 AM
To: Daniel Gerard; [email protected]
Subject: Re: [Sepsis Groups] LR vs NS for fluid

Daniel,

I sent this answer out to the group regarding a question on colloid use.


A perspective of a physiologist,

One to three is the classic crystalloid to colloid ratio and probably good
to use for equivalent volume expansion of colloid to crystalloid. But
crystalloid expansion is quite transient and colloids are more sustained.
This is both good and bad depending on concerns about volume overload.

I would say that for clinical use 6% albumin and most starches are similar
as to volume expansion.

I believe our clinicians use LR first and only go to albumin when LR is
not effective and they don't use any fixed rules.

Also, I believe they prefer LR over NS due to hypercholremic acidosis with
large volume loads.  I would say that plasmalyte is best crystalloid, but
I don't see that it is used here much.

At our institution, in ICU and OR it is almost always albumin as the
colloids and ratios of 1/2 or 1/3 are typically used.  There is strong
evidence about the dangers and limitations of starches due to renal
complications.


George,

George Kramer, PhD
Resuscitation Research Lab
Dept. of Anesthesiology
UTMB, Galveston
409-939-3040






On 2/10/14 5:50 PM, "Daniel Gerard" <[email protected]> wrote:

>Im interested in adding LR as an option for fluid resuscitation, both for
>the saline availability issue and the problem with hyperchloremic
>acidosis from NS. Is there any issue with altering serum lactate levels
>when using large amounts of LR for fluid?
>
>Daniel Gerard RPh
>Critical Care Pharmacist
>McLaren Northern Michigan
>Petoskey, MI 49770
>231-487-4770
>[email protected]
>
>
>
>
>
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