I would like anything for SNF as well.
Thank you,
Amy
From: Sepsisgroups [mailto:[email protected]] On 
Behalf Of Messineo, Laura
Sent: Tuesday, August 05, 2014 1:08 PM
To: Walker, Patricia Ann; [email protected]
Subject: Re: [Sepsis Groups] Combination therapy with Vancomycin given within 
TOP

Does anyone have any SNF sepsis screening tools you would be willing to share?
Thanks,
Laura Messineo

Laura Messineo RN BS
System Manager eICU Operations

Presence Health
1000 Remington Blvd Suite 100 | Bolingbrook, Illinois 60440
Office: 630.914.2905 | Fax: 630.914.2901
[email protected]<mailto:[email protected]>
www.presencehealth.org<http://www.presencehealth.org>

From: Sepsisgroups 
[mailto:[email protected]]<mailto:[mailto:[email protected]]>
 On Behalf Of Walker, Patricia Ann
Sent: Monday, August 04, 2014 9:00 PM
To: '[email protected]'
Subject: [Sepsis Groups] Combination therapy with Vancomycin given within TOP

Hello,

Based on our patient population (elderly and SNF) , our hospital tends to 
frequently utilize Vancomycin. We are seeing cases were Vanco is administered 
in the ED after Blood cultures were drawn but administration is still within 3 
hours of TOP, also a combination of broad spectrum antibiotics are administered 
but not within 3 hours of TOP. The addition of the second agent has been 
determined by a physician's judgment of the patient's severity of illness.

My question is based on literature where combination therapy is advocated in 
critically ill patients with severe sepsis or septic shock.

My question:  Can we answer yes for meeting the bundle based on the fact that 
Vanco was given within 3 hours of TOP, and a broad spectrum antibiotic was also 
administered, but the broad spectrum antibiotics of the TOP 3 hour window.



Some literature found

Antibiotic therapy should be narrowed to target the isolated pathogen when 
culture results become available. Patients who have milder forms of infection 
may be more appropriately treated with narrow spectrum agents and
antibiotic choices in these patients should be based upon current guidelines 
and clinical judgment. De-escalation to a single active agent is strongly 
recommended when culture and susceptibility results return.

4. C. difficile colitis should be treated with enteral antibiotics
if tolerated. Oral Vancomycin is preferred for severe disease
(grade 1A).

Rationale. In adults, metronidazole is a first choice; however,
response to treatment with C. difficile can be best with enteral
Vancomycin. In very severe cases where diverting ileostomy or
colectomy is performed, parenteral treatment should be considered
until clinical improvement is ascertained (539-541).


Thank you,
Patricia Walker, RN-BC. BSN
Evidence Based Practice Manager
924 Westwood Blvd., Suite 900 Los Angeles, CA  90095
T 310.794.8522 F 310.794.3284
"The character of a nurse is just as important as the knowledge he/she 
possesses."
- Carolyn Jarvis



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