Hopefully Brooks will have time to consider and comment on this.
I have long been interested in protocols that will efficiently attack
biofilm infections. It seems that inhaled (nebulized) liposomal medications are
very effective in penetrating very difficult to treat lung biofilms. Some
recent studies have suggested that liposomal antibiotics are superb treatments.
Here is one:
http://jac.oxfordjournals.org/cgi/content/full/61/4/859
The above study used a compressor type of nebulizer (nebulizer PARI LC
Star). Anyway, I would like to try liposomal colloidal silver in a nebulizer
for biofilm lung infections, particularly in racehorses. Normally we use
ultrasonic nebulizers as opposed to the older compressor type nebulizers as was
used in the above study. Ultrasound nebulizers vaporize the medication into
super small droplets that can be pushed into the lung via an air jet. The older
compressor type uses a small air compressor to vaporize the inhaled medication
producing larger medication particles to be breathed in. Naturally, the
ultrasound nebulizer technology produces small droplet size which is more
conducive to lung inhalation efficacy.
What I would like to know, do you see any problems with producing colloidal
silver liposomes using your home made protocol and (2) would an ultrasonic
nebulizer be detrimental to the liposomal structure? Would an older compressor
type nebulizer as used in the study be better in putting liposomes into
solution for inhalation purposes or would the newer utrasonic nebulizers not
over-whelming affect liposomal structure upon vaporzation or might it even be
beneficial?
As a side note, I want to add that heavy metals seem particularly effective
against biofilms of which I would venture a guess that colloidal silver would
be a superb medication, if one could only get it to be absorbed by the biofilm.
Liposomal technology may be the key!
doug
