Oral bromelain was reported to be very effective in potentiating
antibiotics.  I think this is due to it's action in
penetrating/dissolving biofilms, or some similar action.

Dan

On Tue, Jan 19, 2010 at 9:47 AM, polo <[email protected]> wrote:
> Hopefully Brooks will have time to consider and comment on this.
>
>     I have long been interested in protocols that will efficiently attack
> biofilm infections. It seems that inhaled (nebulized) liposomal
> medications are very effective in penetrating very difficult to treat lung
> biofilms. Some recent studies have suggested that liposomal antibiotics are
> superb treatments. Here is one:
>
> http://jac.oxfordjournals.org/cgi/content/full/61/4/859
>
>
>     The above study used a compressor type of nebulizer (nebulizer PARI LC
> Star).   Anyway, I would like to try liposomal colloidal silver in a
> nebulizer for biofilm lung infections, particularly in racehorses. Normally
> we use ultrasonic nebulizers as opposed to the older compressor type
> nebulizers as was used in the above study. Ultrasound nebulizers vaporize
> the medication into super small droplets that can be pushed into the lung
> via an air jet. The older compressor type uses a small air compressor to
> vaporize the inhaled medication producing larger medication particles to be
> breathed in. Naturally, the ultrasound nebulizer technology produces small
> droplet size which is more conducive to lung inhalation efficacy.
>
>     What I would like to know, do you see any problems with producing
> colloidal silver liposomes using your home made protocol and (2) would an
> ultrasonic nebulizer be detrimental to the liposomal structure? Would an
> older compressor type nebulizer as used in the study be better in putting
> liposomes into solution for inhalation purposes or would the newer utrasonic
> nebulizers not over-whelming affect liposomal structure upon vaporzation or
> might it even be beneficial?
>
>     As a side note, I want to add that heavy metals seem particularly
> effective against biofilms of which I would venture a guess that colloidal
> silver would be a superb medication, if one could only get it to be absorbed
> by the biofilm. Liposomal technology may be the key!
>
> doug


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