Good point A baby fish is at one time a single celled organism [?] On Mon, Aug 23, 2021 at 3:11 PM Max <[email protected]> wrote:
> The abstracts I read suggest that silver is toxic to fish embryos and > adult fish at relevant silver concentration levels. Nanoparticles appear > less toxic than ions. But the particles go everywhere, even the brain, and > release ions. A noted cause of mortality to adult fish is disruption of > sodium uptake in the gills. In embryos, free radical damage and DNA > damage cause distortions and dysfunction. > > If my goal is to kill microbes and fungi with silver, then I would want to > somehow maximize the toxicity to certain life forms and reduce toxicity to > a minimum for other life forms. Capping with herb extracts seems like one > promising approach. Limiting doses to periods of time might be wise. > > a concentration of 3 ug/cm2 killed all the fish in this study > > Silver nanospheres are cytotoxic and genotoxic to fish cells > https://pubmed.ncbi.nlm.nih.gov/20060603/ > > ==================================== > Bianchini et al believe that > > 'Acute silver toxicity in aquatic animals is a function of sodium uptake > rate' > Adalto Bianchini > > "the key mechanism of acute silver toxicity consists of reduction in Na+ > uptake by blockade of gill Na+,K+-ATPase;" > ==================================== > whereas Sayed et al find that the toxicity of silver nanoparticles in C. > gariepinus embryos is caused by oxidative stress and genotoxicity. The > embryos were distorted at the nanogram per liter level > > "Embryos were treated with (0, 25, 50, 75ng/L silver nanoparticles) in > water." > ===================================== > Gagne et al report a difference in toxic mechanisms between nanoparticle > and ions, with nanoparticle inducing lipid peroxidation, changes to genes > and inflammation and dissolved Ag involved oxidative stress and protein > stability > 'Toxicity of silver nanoparticles to rainbow trout: a toxicogenomic > approach' > ====================================== > Asharani et al report distorted and malfunctioning fish embryos in > > 'Toxicity of silver nanoparticles in zebrafish models' > > "A concentration-dependent increase in mortality and hatching delay was > observed in Ag-np treated embryos. Additionally, nanoparticle treatments > resulted in concentration-dependent toxicity, typified by phenotypes that > had abnormal body axes, twisted notochord, slow blood flow, pericardial > edema and cardiac arrhythmia." > > > > On 8/23/2021 10:27 AM, Max wrote: > > Thanks Ode > > So what is the toxic level of silver in water to fish? And the toxic > level in drinking water to humans? > > Thanks > > Max > On 8/23/2021 4:11 AM, Ode Coyote wrote: > > Fish rely on microbes to purify their water...kill the microbes...kill the > fish with toxic fish poop and urine water [it wasn't the silver that did it] > > >
