----- Original Message ----- From: Marshall Dudley <[email protected]>
> Very interesting. This contracts information I had read earlier that > indicated that it does not cross the blood brain barrier. I wonder if they > did any quantitative studies, so we could find out if only small amounts > cross, or if it is more open. I wonder what form the silver was in. IE. > maybe it crosses for silver compounds for not for colloid, or vice versa. > > Marshall Would need to read full text for quantitative information. Silver was introduced as silver lactate but was found as silver sulphide. Studies show that silver salts have different action to silver colloids: ========================= The interaction of colloidal metals with erythrocytes. J Inorg Biochem, 56: 4, 1994 Dec, 283-90 Abstract The interactions of citrate reduced colloids (Ag, Au, and Bi) with intact erythrocytes and erythrocyte lysate have been studied by 1H spin echo NMR. Silver colloid is observed to induce cellular depletion of cytosolic glutathione and bismuth colloid induces cytosolic glutathione oxidation in the intact cell. In comparison, there is no detectable effect with gold colloid. With red cell lysate the three colloids all remove glutathione from the spectrum. The metal salts AgNO3 and NaAuCl4 both oxidize intracellular glutathione to diglutathione whereas BiO(NO3) has no effect. Thus colloidal preparations have a different reactivity to their parent metal salts. The differences observed between the three types of colloids (silver, gold, and bismuth) are unique to the colloids studied. None of the colloids studied were biologically inert in the erythrocyte model used. Garner M; Reglinski J; Smith WE; Stewart MJ Language of Publication English Address Department of Pure and Applied Chemistry, Strathclyde University, Glasgow, Scotland, U.K. Unique Identifier 95147010 MeSH Heading (Major) Bismuth [*PD], Colloids, Erythrocytes [*DE/ME], Gold Colloid [*PD], Silver [*PD] MeSH Heading Citrates, Glutathione [BL], Human, Nuclear Magnetic Resonance, Oxidation-Reduction, Silver Nitrate [PD], Support, Non-U.S. Gov't ================================ But the colloids used here are reduced and I really don't understand what's happening. If the colloids are metallic silver, then this does have a biological action. Also the tests sound like they were done in the test tube. The depletion of cellular glutathione probably indicates the heavy metal chelating properties of glutathione. Glutathione has important antioxidant properties and perhaps supplementation of this or alpha lipoic acid would be beneficial. What this says about crossing the blood brain barrier, beats me <g> I don't know why I mentioned it... but if ionic colloid particles are reduced to single ions in digestion or in the body, then there is no reason not to suppose that they also cross the barriers. Ivan -- The silver-list is a moderated forum for discussion of colloidal silver. To join or quit silver-list or silver-digest send an e-mail message to: [email protected] -or- [email protected] with the word subscribe or unsubscribe in the SUBJECT line. To post, address your message to: [email protected] Silver-list archive: http://escribe.com/health/thesilverlist/index.html List maintainer: Mike Devour <[email protected]>
