This is in response to several postings.

Wayne said,
“My voltage is about 1/2 as much, 52 VDC vs your 110
VDC. The volume is 60 oz or about 1/2 gallon. If my
starter and water was the same as yours, then the one
hour should give me about the same ppm, it would
appear. Is this logic flawed, or is there something I
am missing?“

Your logic sounds good to me.

Jrowland said,
“It would seem that in some instances, the CS target
would be such that the smallest possible silver
particle size might be needed. What method of
production would you use, and any idea how small a
size can be had?“

I have read that .001 micron is 1/7,00th the size of a
red blood cell. I have also read that when the silver
particles get much bigger than that, they begin to
refract light (giving the CS a yellowish color). So my
reasoning is that crystal clear CS has particles (or
ions) too small to need it any smaller. Or, in other
words, after a certain point, the CS particles are as
small as is needed for any assimilation process in the
human body.

John Reeder said,
“If you don't have starter, how long will it take?”

On the average, I found that using 1/4 CS as a starter
reduced my brewing time by 1/2 to 2/3. If I needed to
make a batch but had no starter, I would make a quart
of starter first, which would take about 1 to 1-1/2
hours. Even if my starter batch is yellow (unless dark
yellow), it makes good starter, and the end batch is
still clear.

To comment on other posts, we seem to have accepted a
list members story of apparent argyria without
identifying the factors involved. How much CS did this
person ingest? Over what period of time? What ppm was
it? There was some talk of it being made by WaterOz,
but does anyone know how they make their CS? Folks
even talk of argyria being something they had and then
‘got over’, which is not considered to be possible.
Has this person been medically diagnosed as having
argyria? I have a very difficult time believing
someone has argyria from a modest or reasonable
quantity of colloidal silver, even silver compounds
such as Mild Silver Protein. Every other case of
argyria on record describes incidents of argyria as a
result of ingestion or exposure to extremely high
levels of silver compounds or silver dust (such as
with a silver-smith).

The following is for the benefit of those who are new
to the list, who have not read this before. None of
this is new to the ‘Old-timers’.

Let me quote Alexander G. Schauss, Ph.D.
Director, Life Sciences Division
John Hopkins University                               

“…you should be advised that we recently completed an
extensive review of the scientific literature on the
safety of silver, especially as it relates to its one
known potential side effect, namely, Argyria. Argyia
is an irreversible discoloration of the pigment (skin)
caused by excessive silver intake or chronic exposure
to silver by certain tissues. The amount of silver
required to develop Argyria is estimated to be 3.8
grams per day.  By comparison standard 10 ppm
colloidal silver contains silver in amounts equaling
less than 1 milligram of silver (1,000 micrograms = 1
milligram; 1,000 milligrams - 1 gram), which therefore
represents an amount approximately 1/500th to 1/1000th
of the amount of silver considered to be a risk in the
development of Argyria.

“Most cases of Argyria reported in the medical
literature over the last 100 years involved chronic
intravenous or intramuscular use of the silver
preparations, most often involving a silver drug
prescribed by physicians which in most cases contained
silver nitrate. Other cases of Argyria reported in the
medical literature involve application of silver
preparations used for many months or years in the
treatment of the eye or vagina for certain diseases.
We could not locate a single case of orally consumed
colloidal silver manufactured in the last 25 years
causing Argyria in our review of the literature. This
is probably due to the low levels of silver contained
in such preparations, since only very small amounts of
silver are needed for its antiseptic effect.

“Humans consume approximately 100 micrograms of silver
every day in the diet. Additional amounts within this
range would be considered safe by all reasonable
estimates, especially if the amount needed to develop
Argyria would be equivalent of 380,000 micrograms (or
3.8 grams) of silver a day.”

To better understand the misconception regarding
Argyria, I will quote from the book "The Micro Silver
Bullet”™ by Dr. M. Paul Farber 1996 page XII (ISBN
1-887742-00-X)  In reference to a "Journal of American
Medical Association" article, October 18 1995, volume
274 # 15, where cases of Argyria were cited to have
been caused by silver compounds (not colloidal silver,
but silver mixed with other metals), note:

"These Case history presentations represent biased and
unprofessional writing. The author's apparent
inability to understand the difference between a
silver nitrate, sulfide, or other silver compound
demonstrates their lack of understanding of basic
chemical properties. The matrix, substrate, and
particle size are all critical to the varied functions
and reactions with use of these products. That is why
there has not been a single case of Argyria from a
properly manufactured modern-day colloidal silver
product. The cases of Argyria reported in the 1920's
and 1930's resulted because the technology of the day
was unable to produce a pure colloidal silver product
with a small enough particle size." 

In reference to possible silver toxicity, Dr John Hill
D.C. in his book “Colloidal Silver, A Literature
Review” states this:

“Critics of colloidal silver sometimes state that it
has been known to cause organ damage, kidney damage,
pulmonary edema, atherosclerosis and death.

“These claims appear to be based on a research study
on dogs in which the dogs were deliberately killed by
extremely large lethal doses of silver. At the doses
given, any heavy metal and probably many essential
minerals like zinc, iron, copper, etc. would have
produced death in similar fashion."

And again, "We know that dogs died from injections of
a type of protein-bound silver in dosages ranging from
500 mg to 1.9 grams of silver, depending on the
frequency of administration. This was equivalent in
silver content to giving [per day] a 150 pound adult
between 150 litres and 570 litres of 10 ppm colloidal
silver, or between 75 and 285 liters of 20 ppm
colloidal silver or between 50 and 190 litres of 30
ppm colloidal silver. The 10 gram estimated lethal
dose for humans from Goodman and Gillman is equivalent
to 1000 liters of 10 ppm colloidal silver. In another
case an individual ingested an estimated 124 grams of
silver nitrate over a 9-year period. She developed
argyria and an assortment of neurological symptoms as
well... This report is often used by critics to
attribute neurological disorders to silver
consumption. They curiously fail to put in perspective
the gross difference between the quantities of silver
involved."

Thus colloidal silver cannot cause argyria.
Theoretically I guess one could take CS with
sufficient ppm and in sufficient quantity to cause
aggregation, but one would likely drown from too much
water first, as the amounts would be truly phenomenal.

In years of pouring over hardcopy of obscure medical
cases no one has yet found a single report of any
adverse reaction to very fine particles of very fine
silver floating in very pure water.

The following two letters to and from the USFDA are
most informative:

October 14th, 1999 
Food and Drug Administration
U.S. Department Of Health and
Human Services
Public Health Service
5600 Fishers Lane
Rockville, MD 20857

Dear Sirs/Madam,

Pursuant to the Freedom of Information Act and in
regard your August 17th, 1999 ruling regarding
colloidal silver, could you please supply the
following documentation on which you based your
decision?

1. The number of deaths related to the consumption of
colloidal silver.

2. The number of allergic reactions to the consumption
of colloidal silver.

3. The number of harmful drug interactions from both
OTC and prescription drugs when combined with
colloidal silver.

4. The number of reported cases of Argyria from
colloidal silver made with the AC or DC electrical
process.

5. The number of cases of Argyria from colloidal
silver that did not contain protein stabilizers. 

Thank you for your time and consideration of this
request.

Sincerely,
Brent Finnegan

The FDA response:

Public Health Service
Center for Drug Evaluation and Research
Office of Training and Communication
Freedom of Information Staff HFD-205
5600 Fishers Lane 12 B 05
Rockville, Maryland 20857
DEPARTMENT OF HEALTH AND HUMAN SERVICES

November 3, 1999

In Response Refer to File: F99-22589
Brent Finnigan Takoma (sic), WA 98408

Dear Mr. Finnigan:

This is in response to your request of 10/14/99, in
which you requested adverse events associated with the
use of Colloidal Silver. Your request was received in
the Center for Drug Evaluation and Research on
10/25/99.

We have searched the records from FDA's Adverse Event
Reporting System (AERS) and have been unable to locate
any cases that would be responsive to your request.

Charges of $3.50 (Search $3.50, Review $0,
Reproduction $0, Computer time $0) will be included in
a monthly invoice. DO NOT SEND ANY PAYMENT UNTIL YOU
RECEIVE AN INVOICE.

If there are any problems with this response, please
notify us in writing of your specific problem(s).

Please reference the above file number.

Sincerely,

Hal Stepper
Freedom of Information Technician
Office of Training and Communications
Freedom of Information Staff, HFD-205


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