Hi Duncan 
I got lost (again) ...
You are saying there are 4 types of glutathione, but
then you are saying GSH and GPx are the most important
forms. I didn't know there are so many types of
glutathione (do you have any basic papers on that?)
and second which is abbreviated by GSH? I thought GSH
= glutathione?

Maia


--- Duncan Crow <[email protected]> wrote:
> Lona, I've seen those advertisements too...
> 
> Cumin may increase glutathione by 700% from what
> level? Note in the study 
> that follows, GST was increased an AVERAGE of 78%;
> it is the form of 
> glutathione increased by several foods including
> cumin, however GSH and 
> GPx are arguably more important glutathione forms as
> they are used in 
> much greater quantities in the body.
> 
> The limiting factor to glutathione production is
> cystine and cysteine-
> containing molecules, and also selenium in the case
> of GPx. Without the 
> precursors present the cells can not make
> glutathione so these precursors 
> will remain the limiting factor for four forms of
> glutathione.
> 
> Not addressing precursor availability would be
> similar in a way, to 
> increasing liver function potential with bitter
> herbs or drugs while 
> ignoring  hepatic stones that block the bile flow
> and necessitate the 
> recirculation of toxic waste produced.
> 
> I found only three peer-reviewed studies in a search
> on cumin AND 
> glutathione. Here's the most applicable:
> __________________________
> Plant products as protective agents against cancer.
> 
> Aruna K, Sivaramakrishnan VM.
> 
> Isotope Division, Cancer Institute, Madras, India.
> 
> Out of various spices and leafy vegetables screened
> for their influence 
> on the carcinogen-detoxifying enzyme,
> glutathione-S-transferase (GST) in 
> Swiss mice, cumin seeds, poppy seeds, asafoetida,
> turmeric, kandathipili, 
> neem flowers, manathakkali leaves, drumstick leaves,
> basil leaves and 
> ponnakanni leaves increased GST activity by more
> than 78% in the stomach, 
> liver and oesophagus, - high enough to be considered
> as protective agents 
> against carcinogenesis. Glutathione levels were also
> significantly 
> elevated in the three tissues by these plant
> products. All of them except 
> neem flowers, significantly suppressed (in vivo) the
> chromosome 
> aberrations (CA) caused by benzo(a)pyrene in mouse
> bone marrow cells. 
> Multiple CA and exchanges reflecting the severity of
> damage within a cell 
> were significantly suppressed by these nine plant
> products. The results 
> suggest that these nine plant products are likely to
> suppress 
> carcinogenesis and can act as protective agents
> against cancer.
> 
> PMID: 2283166 [PubMed - indexed for MEDLINE] 
> _______________________
> 
> Duncan Crow
> 
> > I have read the Cumin increases your levels by
> 700%.
> > Lona
> > 
> 
> 
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