Debbie- I mix the MSM right in with the CS at the time of treatment. Like 1/2-1 teaspoon or so...I don't use distilled water in the treatment, just CS. This is just how I do it. Also I like to mix the CS with the MSM just for the amount I am going to use for the treatment. Below is some info on MSM and DMSO from a web page... http://www.krysalis.net/dmso.htm Hope this helps, Rob
DMSO is a widely used commercial solvent derived from trees (living plants) as
a byproduct from the production of paper. There are so many claimed health
benefits from its use, one has to wonder if it doesn't perform a similar vital
function in the biochemistry of plants. If so, it may be no accident that it
can provide such broad ranging health benefits to us. It has been written up in
many places such as the recent book "DMSO, Nature's Healer" by Dr. Morton
Walker (1993), and by Dr. Julian Whitaker in his newsletter "Health and
Healing" in the August, 1995 issue. It is sold in many if not most health food
stores in the US and in most countries around the world. Apparently it is used
by millions of people for its health benefit properties. I have also found it
has a profound beneficial effect in the treatment of Crohn's Disease as
discussed in an earlier Health Note. It is commonly used for treating animals,
horses in particular, but the FDA has approved it for only one use for humans,
the treatment of interstitial cystitis. Since so many people use it anyway,
this has made it a controversial subject. Possibly one reason for this is that
no one has ever explained how it works biochemically. If that can be done, it
should take it out of the controversial "magic" health benefit classification,
and put it on a sound technical foundation. It is the purpose of this Health
Note to present my new insight/views into that needed description of the
primary biochemical function of DMSO in combination with its spontaneously
created oxidized form, MSM.
In the Health Note for Crohn's Disease I describe a mechanism where the DMSO
stimulates a mechanism that enhances the transport of iron from the intestine
to the rest of the cells in the body. This is a very specialized mechanism,
which is not the primary health benefit mechanism that will be discussed here.
The primary mechanism discussed here is how I believe DMSO, in combination with
its spontaneously generated oxidized form, MSM, act as an antioxidant pair, in
the same sense as I discuss other antioxidants in the previous Health Note, in
other words the biochemistry of how DMSO and MSM act together to enhance
metabolism.
Oxidation States of DMSO
In the body, DMSO can and does take three different oxidation states. It is
useful to think of them as being in equilibrium, with the distribution between
them at any point being determined by the localized conditions that exist
within the cells. The first oxidation state is DMSO itself which has one oxygen
atom attached to the sulfur atom. The other two are 1) dimethyl sulfone, also
known as methlysulfonylmethane (MSM), which is DMSO with an additional oxygen
atom attached to the sulfur atom, forming a molecule with a total of two
attached oxygen atoms, and 2) dimethyl sulfide which is DMSO with the oxygen
atom removed, forming a molecule with no oxygen's attached. Both DMSO and MSM
have the property of being quite soluble in both oil and water based liquids.
However, dimethyl sulfide is hydrophobic and tends to be insoluble in water and
soluble in oil based liquids.
DMSO and MSM
It should be mentioned here that dimethyl sulfone, the oxidized form of DMSO,
is just the more commonly used chemical name for methlysulfonylmethane (MSM)
which is now readily available in health foods stores, and which many claim to
greatly enhance energy. According to my theory presented here, DMSO and MSM,
which form each other in the body, should be essentially indistinguishable in
their biochemical effects. They reach a equilibrium distribution between them
that is dependent on the local body chemistry, and is independent of which one
you start with.
The Metabolic Enhancement (Antioxidant) Mechanism of the DMSO-MSM Pair
The metabolic enhancement mechanism of DMSO (or MSM) is that of an
exceptionally effective oxygen transport system. This transport system involves
only two of the three oxidation forms, DMSO and dimethyl sulphone (also known
as MSM). If we consider both DMSO and MSM coexisting in equilibrium within the
body, (as they always would no matter which you started with) and recognizing
that different parts of the body have different oxidation potentials. Then, as
the combination is exposed to a zone of high oxidation potential, DMSO is
oxidized to MSM resulting in a new distribution of DMSO and MSM which is higher
in MSM. Then as the combination moves to a zone of lower oxidation potential,
the MSM releases its oxygen, delivering it to the metabolic processes,
resulting in a new distribution that is higher in DMSO again. The cycle then
repeats itself and in doing so, serves as an exceptionally effective oxygen
transport system. This system could be operative on a macro scale, enhancing
the transport of oxygen from the lungs to the blood, from the blood to the
cells, and on a micro scale within the cells transporting high oxidation
potential to the lower oxidation potential of the mitochondria where it is used
in metabolism. We have a continuously decreasing oxidation potential starting
highest at the entry point, the lungs, lower in the blood, lower yet as it
enters the cells, continuously lowered in the sequences of the metabolic
reactions, and finally lowest of all as it is excreted as carbon dioxide and
water, the products of metabolism. The DMSO-MSM system of transport will
operate only at the front end, delivering oxygen to the mitochondria. It is
unlikely that it will play a significant role after the oxygen has been
delivered to the mitochondria and the complex metabolic reaction sequences
start.
-----Original Message-----
From: Jack Dayton [mailto:[email protected]]
Sent: Wed 11/5/2003 2:43 PM
To: [email protected]
Cc:
Subject: Re: CS>DMSO/MSM
kittykat 11/4/03 3:35 PM Wrote:
> After reading Rob's comments regarding helping his sister's asthma,
perhaps
> I should start adding MSM instead of the DMSO first.
*********************
I can't answer that, I don't know if MSM has the
same transdermal ability as DMSO, probably some
other, more knowledged member, will elucidate.
But if you wish to buy MSM as a powder which you
can then make up a portion as a liquid just start slowly
adding MSM to DW until no more MSM will liquefy.
I started with 8 oz of DW and I think it was about
the 4th or 5th scoop (a scoop comes in the can) that
no more would liquefy - pour off the liquid, and discard
what's left in the bottom.
I probably would be a good idea to rinse the containers
used for mixing with CS to sterilize things.
I bought my MSM from the following supplier that I have
dealt with for many years - very reliable. To go directly to
the page - copy and paste:
http://www.swansonvitamins.com/shopItemDetail.asp?txtQueryID=sw851&txtProduc
tID=SW851&selCategory=&txtKeyword=&selPrice=&abspage=1&SID=&SourceCode=INTL0
07&vendor=&selSortOption=&selHealthDropdown=&shopperid=P6HXG57440S92H4300AKH
8LW30J17SDE
See why I suggested copy & paste?
Good luck, and be careful.
Jack
Be Nice
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