------------------------------ Date: Sat, 07 Feb 2004 19:50:29 -0600 From: Wayne Fugitt <[email protected]> To: [email protected] Subject: CS>Eye Formulation Question Message-id: <[email protected]> Content-type: text/plain; charset=us-ascii; format=flowed Content-transfer-encoding: 7BIT
In the Feb issue of Second Opinion by Dr. Robert J. Rowen, he has some interesting comments about an eye formula that has helped some people with cataracts. This description concerns oral carnosine (as L-Carnosine), carnosine eye-drops (as N-acetylcarnosine) and topical carnosine (as Beta-Alistine®). Carnosine (not to be confused with Carnitine) is a natural amino-acid that has been known about for decades. But it is only through recent Australian and British clinical and laboratory studies that the benefits of carnosine have become better known. Carnosine has a number of interesting actions, it is a potent anti-oxidant, it helps to chelate ionic metals (i.e. flush toxins from the body), it has immune boosting properties (aid's wound healing) and is also known to reduce and prevent cell damage caused by beta amyloid (the substance found in the brain of Alzheimer disease patients). Carnosine helps protect neural tissues by blocking and inactivating beta amyloid and therefore it could help protect tissues against dementia. Recent evidence even suggests that carnosine has a important role in the sense of smell. >From the anti-aging standpoint, there are some very interesting carnosine actions, they are: * Carnosine's ability to help prevent glycosylation- the cross linking of proteins (and DNA molecules) caused by sugar aldehydes reacting with the aminoacids on the protein molecule and creating Advance Glycosylation End-products (AGE's). If you want to see protein cross linking in action cut an apple in half and watch it turn yellow! Such anti-glycosylation may be beneficial for diabetes, cataracts, neuropathy, kidney failure and skin conditions, as well as "general" anti-aging properties, especially improving skin condition. * In 1999, Australian researchers confirmed that carnosine increases the longevity of human fibroblast cells in the laboratory. Carnosine extended the Hayflick limit (the maximum number of times a cell can divide), from a "normal" 50 by up to an additional 10 times! Although not enough time has passed to test these results, carnosine may be a supplement of choice for longevity. It has been shown that animals with higher levels of carnosine appear to live longer than their controls. * The Russians use Carnosine (in an eye-drop form) to help eradicate senile cataract problems with great success, (their clinical trials indicate an eye-condition improvement of 41.5% to 100% for patients within a 6-month period with sustainable results 24-months later). This type of carnosine eye-drop may have very important anti-aging eye functions because it is breaking protein cross-links, NOT just inhibiting them. Note however, that the Russians have been using a "special" kind of carnosine known as N-alpha acetylcarnosine or NAC for this purpose. It is not "just" L-carnosine as an eye-drop. Dr. Mark Babizhayev, one of the scientists behind the Russian clinical trials stated; "L-carnosine means nothing for the treatment of human cataracts because it readily becomes hydrolyzed with the serum carnosinase in the aqueous humor.Besides, L-carnosine appears even dangerous for the treatment of ocular disorders, as it gradually releases histamine via the activity of histidine decarboxylase." The NAC eye-drops to be used for the treatment of cataract require 2-drops into each eye, twice daily for a period of 6-12 months (although due to the nature of senile cataract a permanent continuance may be advisable). Dr. Babizhayev in his interview states that the best results are achieved in the 3 to 5 month period. For preventative use, 1-drop into each eye daily with frequent breaks may be more practical. To date no serious side effects have been noted in any of the trials, (this is probably because the Russians have developed a unique form of N-acetylcarnosine eye-drops, whereby they have removed the majority of metals and salts, thereby reducing the possibility of side-effects). Carnosine oral supplementation is a relatively new area, normal current anti-aging dosages are 50mg-150mg of L-carnosine per day, (maximum 200mg day) with occasional breaks. Such dosages have failed to produce any report of serious side effects or contraindications to date. -- The Silver List is a moderated forum for discussing Colloidal Silver. Instructions for unsubscribing are posted at: http://silverlist.org To post, address your message to: [email protected] Silver List archive: http://escribe.com/health/thesilverlist/index.html Address Off-Topic messages to: [email protected] OT Archive: http://escribe.com/health/silverofftopiclist/index.html List maintainer: Mike Devour <[email protected]>
