Hi, Deborah,

If any ensemble of informed, willing human volunteers
participated in the hypothetical experiment, some
would exhibit herxing and some would not. A statistical
treatment of the outcome (e.g. perhaps a contingency
table test) may allow an inference to be drawn on
the question of presence or absence of silver in the
blood. This would be an ethical approach, or at least
more ethical than a controlled experiment on a
single human. And lab animals would be spared.

Thanks for your thoughtful critique.

Best regards,

Matthew