The review text Argyria And The Pharmacology Of Silver by Hill and Pillsbury (1939) mentions the chief studies of bioaccumulation of silver in children, infants and fetuses as being that of J.H. Sheldon and H. Ramage in 1933. See Proceedings of the Royal Society of Medicine, 113:308. See also Biochemistry Journal, 27: 674, 1933 and Biochemistry Journal 25: 1608, 1931. Hill and Pillsbury summarize the findings of Sheldon and Ramage on page 22 of their treatise: "Sheldon and Ramage concluded from their studies that the appearance of silver in human tissues does not appear to be related to the age of the individual." Hill and Pillsbury further note on page 23 that "little conclusive data as to the comparative amounts of silver found in various organs is available in the literature previous to 1930." On page 42, Hill and Pillsbury note that in cases of argyria, "...there is abundant evidence to indicate that silver is deposited in the majority of the structures of the body in argyria, with the possible exception of nerve tissues and muscle." -------------------------------------------------------------------------------- Scanned for virus by McAfee WebShield e500 Appliance
