I get bulk MSM from www.msm-msm.com and their directions say: Start with 1/8 to 1/4 tspn per day.Gradually increase up to 6 to 8 tspns/day over several weeks.Then drop back to 1 or 2 tspns../day.For best results take 500 to 1000 mgs a day of ester C per tspn of MSM up to 3000 mgs/day.Drink plenty of water[very important] If any flu symptoms accur,reduce,but do not stopMSM.Increase water,then slowly increase MSM. I have been using it this way for a couple of years now,up to three,four teasoons/day.Instead of ester c ,I use calcium ascorbate crystals and a teaspoon of Xylitol to make it more palatable. Harold
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