You can do that with a SLURM job submit plugin. I would recommend  
doing it with a script. More information here:
http://www.schedmd.com/slurmdocs/job_submit_plugins.html

Quoting Daniel Adriano Silva M <[email protected]>:

> Hi Developers,
>
>  In order to reduce cluster fragmentation, when using QOS, is there any way
> to enforce that the requested CPUs are multiples of certain number? For
> example, equivalent to always fill complete node(s)?  In a way that in a
> Cluster composed by nodes with 8 CPUs the jobs request should be:  8, 16,
> 24, etc, CPUs in order to be accepted.
>
> Thanks,
> Daniel
>

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