Thanks for the VC tips. Where can I upload the BSA file?

Moyez

On Mar 16, 5:25 pm, Natalie Tasman <[email protected]> wrote:
> Hi Moyez,
>
> Of course we have our own files to test, but yes, please upload your
> file, as we've never observed the behavior you're reporting.
>
> And also please rerun your conversions with the "-v" (verbose) option
> and copy and paste the output up to the "sha-1" calculation.
>
> You're welcome to rebuild and debug the converter on your own.  Just
> open the TPP.sln file and build the mzWiff project from there.  Note
> you'll also need the "win_lib" project to be checked out at the same
> level as the TPP code for boost, zlib, etc.
>
> -Natalie
>
>
>
> On Mon, Mar 16, 2009 at 2:07 PM, Moe <[email protected]> wrote:
>
> > Hi Natalie,
>
> > The leak is apparent in QStar WIFF files of any size. For a 30 minute
> > BSA QC run (25 MB file size), peak memory usage reached 314 MB (to
> > produce ~195 MB mzXML output), which doesn't seem reasonable. Do you
> > have your own data files that you can debug with? If not, I can upload
> > the BSA run to your FTP site (need the details).
>
> > The data I'm trying to analyze consists of 2 hour runs at about 500 MB
> > each. mzWiff crashes about halfway through a data file, leaving a 1.3
> > GB (incomplete) mzXML file which ends at an elution time of about 60
> > minutes (when memory reaches slightly > 2 GB).
>
> > I have tried older releases of the executable up to 4.0.0 and all
> > behave the same. I am considering recompiling a 64-bit executable, or
> > trying to locate the leak. I'll check out the code from SourceForge,
> > but if you have additional instructions for setting up the VC project,
> > please let me know.
>
> > Thanks,
> > Moyez
>
> > On Mar 16, 1:41 pm, Natalie Tasman <[email protected]> wrote:
> >> Hello Moyez,
>
> >> Thank you for the detailed bug report.  I haven't heard of issues with
> >> mzWiff.  Thanks for the MSVC hint-- I'm pretty sure this is not turned
> >> on yet, but actually probably shouldn't be necessary.  I agree with
> >> you that that much memory usage sounds like a memory leak.  The
> >> converters are designed to process data scan-by-scan with a relatively
> >> low memory overhead.
>
> >> If you can upload a sample file we can take a look and see if we can
> >> replicate behavior and then fix it.
>
> >> Thanks,
>
> >> Natalie
>
> >> On Mon, Mar 16, 2009 at 9:11 AM, Moe <[email protected]> wrote:
>
> >> > I'm trying to convert Analyst QStar Elite data acquired with Analyst
> >> > QS 2.0, with mzWiff version 4.2.0(build Feb 19 2009 09:48:08), on
> >> > Windows XP Pro SP3 and Windows Server 2003 R2 x64 Standard SP2.
>
> >> > There appears to be a memory leak causing process memory to accumulate
> >> > to > 2GB, shortly after which the program crashes with error:
>
> >> > ERROR: COM error 80004005 while processing sample#2
> >> > INFO: error message: Unspecified error
>
> >> > This happens both on 32-bit XP and 64-bit Server 2003, both systems
> >> > have > 4GB physical memory. The per-process addressable limit for a 32-
> >> > bit process is 2GB unless compiled with the /LARGEADDRESSAWARE Visual C
> >> > ++ linker flag.
>
> >> > Is anyone aware of this problem? Is this in fact a leak that can be
> >> > avoided?
>
> >> > Thanks,
> >> > Moyez- Hide quoted text -
>
> >> - Show quoted text -- Hide quoted text -
>
> - Show quoted text -

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