Hi -

I have just optimized the PQD settings on our Orbi to be able to
analyze TMT/iTRAQ data for the first time. So far, I've been using TMT
along with SorcererSequest/TPP and Libra. All is working great, except
I'm unsure of what types of standard deviations I should be expecting
to see.

I have been testing different m/z tolerances, centroiding types,
minimum threshold values, etc in the condition.xml file, and I get
ratios very close to expected, typically within 5-10% of expected
values for the best settings. However, no matter what I seem to try,
my SD values are never above 0.05, and I was wondering if this is too
'good' to be true?

Anyone have any insight into what sorts of SD I should expect to see?
I'm worried that I'm missing something and that my data may be
misleading.

Thanks!!
Rebekah
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