Hi guys,
I'm experiencing a problem with analyze peptide step in TPP; when I
launch the peptide/protein prophet I get the errore message below,
sometimes it even goes into an infinite loop giving no result at all.
I'd really appreciate any hint.

Best

Filippo


 Command 1 [Fri Jun 12 16:31:10 2009]              [ Show / Hide ]

 run_in j:/Inetpub/wwwroot/ISB/data/enolase_DDA02; xinteract  -
Ninteract.pep.xml -p0.05 -l7 -Op j:/Inetpub/wwwroot/ISB/data/
enolase_DDA02/enolase_DDA02.tandem.pep.xml

C:\Inetpub\tpp-bin\xinteract.exe (TPP v4.2 JETSTREAM rev 0, Build
200902190939 (MinGW))

running: "C:/Inetpub/tpp-bin/InteractParser "interact.pep.xml" "j:/
Inetpub/wwwroot/ISB/data/enolase_DDA02/enolase_DDA02.tandem.pep.xml" -
L"7""
warning: xsl file j:/inetpub/wwwroot/ISB/data/enolase_DDA02/
interact.pep.xsl must begin with the WEBSERVER_ROOT path for use with
a webserver.
 file 1: j:/Inetpub/wwwroot/ISB/data/enolase_DDA02/
enolase_DDA02.tandem.pep.xml
 processed altogether 406 results
problem (ph8): j:/Inetpub/wwwroot/ISB/data/enolase_DDA02/
interact.pep.xml is not mounted under webserver root: c:/Inetpub/
wwwroot/
command completed in 2 sec

running: "C:/Inetpub/tpp-bin/PeptideProphetParser "interact.pep.xml"
MINPROB=0.05"
 (X! Tandem (k-score))
init with X! Tandem (k-score) trypsin
MS Instrument info: Manufacturer: Waters, Model: q-tof micro,
Ionization: ESI, Analyzer: TOFMS, Detector: unknown

 PeptideProphet  (TPP v4.2 JETSTREAM rev 0, Build 200902190939
(MinGW)) akel...@isb
 read in 0 1+, 203 2+, 203 3+, 0 4+, 0 5+, 0 6+, and 0 7+ spectra.
Initialising statistical models ...
negmean = 0.0533258
negmean = -0.898231


...skipping 15 lines of output...

command completed in 1 sec

running: "C:/Inetpub/tpp-bin/DatabaseParser "interact.pep.xml""
command completed in 0 sec

running: "C:/Inetpub/tpp-bin/RefreshParser "interact.pep.xml" "j:/
Inetpub/wwwroot/ISB/data/dbase/
HsIPI3.50_Ec_cRAP_20_TargetDecoy.fasta""
  - Searching the tree...
  - Linking duplicate entries...  - Printing results...

  - Building Commentz-Walter keyword tree...command completed in 10
sec

running: "C:/Inetpub/tpp-bin/PepXMLViewer.cgi -I j:/Inetpub/wwwroot/
ISB/data/enolase_DDA02/interact.pep.xml"
error: unable to read pepxml file: error parsing pepxml file: can't
open index file for output: j:/Inetpub/wwwroot/ISB/data/enolase_DDA02/
interact.pep.xml.index; check permissions

command "C:/Inetpub/tpp-bin/PepXMLViewer.cgi -I j:/Inetpub/wwwroot/ISB/
data/enolase_DDA02/interact.pep.xml" failed: Operation not permitted

command "C:/Inetpub/tpp-bin/PepXMLViewer.cgi -I j:/Inetpub/wwwroot/ISB/
data/enolase_DDA02/interact.pep.xml" exited with non-zero exit code: 1
QUIT - the job is incomplete

command "C:\Inetpub\tpp-bin\xinteract.exe -Ninteract.pep.xml -p0.05 -
l7 -Op j:/Inetpub/wwwroot/ISB/data/enolase_DDA02/
enolase_DDA02.tandem.pep.xml" failed: Operation not permitted

Command FAILED

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