Hi,

I am using TPP version 4.2.1 on windows. My raw file is from Orbitrap.
The process until peptide prophet works smoothly. I am searching with
Mascot against a database that includes decoy entries and no enzyme.
I use the following run options for peptide prophet:  MINPROB=0.05
ACCMASS
The peptide prophet command ends successfully, but in the result
pepXML file all the peptides has a negative probability and when
looking in the plotmodel it is written that "Estimated total number of
correct peptide assignments in dataset: 0.0 ".

Do I use the correct run options? Should I choose other options?

Thanks,
Keren

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