Hello everyone,

I would like to update you regarding my progress with the problem I
had.
I have reinstalled the apache server and the TPP software. After the
reinstalation I have succeeded to get peptide probabilities from
peptide prophet with both X!tandem and Mascot searches. Though the
peptide analysis with the Mascot search results gave an error massage:
 "ERROR: NAN probability density detected.  Please alert the
developer !!!"
I have copied the entire command session below.

Keren.

# Commands for session B7GEOBZV7 on Wed Jun 17 09:23:58 2009
# BEGIN COMMAND BLOCK
###### BEGIN Command Execution ######
[Wed Jun 17 09:23:58 2009] EXECUTING: run_in c:/Inetpub/wwwroot/ISB/
data/Keren/20172; xinteract  -NinteractMascot20172.pep.xml -p0.05 -l7 -
OANFP -d### c:/Inetpub/wwwroot/ISB/data/Keren/20172/
Seq20172_Ilan_E2O2.pep.xml
OUTPUT:

C:\Inetpub\tpp-bin\xinteract.exe (TPP v4.2 JETSTREAM rev 1, Build
200904071723 (MinGW))

running: "C:/Inetpub/tpp-bin/InteractParser
"interactMascot20172.pep.xml" "c:/Inetpub/wwwroot/ISB/data/Keren/20172/
Seq20172_Ilan_E2O2.pep.xml" -L"7""
 file 1: c:/Inetpub/wwwroot/ISB/data/Keren/20172/
Seq20172_Ilan_E2O2.pep.xml
 processed altogether 7958 results


 results written to file c:/Inetpub/wwwroot/ISB/data/Keren/20172/
interactMascot20172.pep.xml

 direct your browser to 
http://localhost/ISB/data/Keren/20172/interactMascot20172.pep.shtml



command completed in 4 sec

running: "C:/Inetpub/tpp-bin/PeptideProphetParser
"interactMascot20172.pep.xml" MINPROB=0.05 ACCMASS NONTT FORCEDISTR
NONPARAM DECOY=###"
using Accurate Mass Bins
Using Decoy Label "###".
Not using ntt model
Forcing output of mixture model
Using non-parametric distributions
 (MASCOT)
results for charge 1: 4588 id tot and 36 adj scores
results for charge 1: -5.94114 adj_ion_mean and 1.49971 adj_ion_hom
mean 49.191id mean0.2783 correlation (r)
1+ ion - id = 2.16102*(ion - hom) + -9.18205 with error = 8.34861
mean ion - id: -5.94114, mean ion - hom: 1.49971
adding Accurate Mass mixture distr
results for charge 2: 3141 id tot and 46 adj scores
results for charge 2: -6.28644 adj_ion_mean and 6.818 adj_ion_hom mean
49.7178id mean0.721109 correlation (r)
2+ ion - id = 1.03256*(ion - hom) + -13.3264 with error = 6.70693
mean ion - id: -6.28644, mean ion - hom: 6.818
results for charge 3: 185 id tot and 0 adj scores


...skipping 1475 lines of output... [ view all ]

ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
ERROR: NAN probability density detected.  Please alert the
developer !!!
command completed in 41 sec

running: "C:/Inetpub/tpp-bin/ProphetModels.pl -i
interactMascot20172.pep.xml"
Analyzing interactMascot20172.pep.xml ...
Reading Accurate Mass Model model +1 ...
Reading Accurate Mass Model model +2 ...
Reading Accurate Mass Model model +3 ...
Reading Accurate Mass Model model +4 ...
Reading Accurate Mass Model model +5 ...
Reading Accurate Mass Model model +6 ...
Reading Accurate Mass Model model +7 ...
Parsing search results "c:/Inetpub/wwwroot/ISB/data/Keren/20172/
Seq20172_Ilan_E2O2 (MASCOT)"...
  => Total of 3190 hits.
command completed in 2 sec

running: "C:/Inetpub/tpp-bin/DatabaseParser
"interactMascot20172.pep.xml""
command completed in 0 sec

running: "C:/Inetpub/tpp-bin/RefreshParser
"interactMascot20172.pep.xml" "c:/Inetpub/wwwroot/ISB/data/dbase/
uniprot_homo09_decoy_appended.fasta""


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