Jimmy,
Just to clarify: the timeout occurs both during the Sequest search and
also during the pepXML conversion. I haven't gotten the time to
reinstall the software in this computer; I hope I can do it sometime
this week.
I'll post my findings once this is completed.
Again, many thanks you for your help,
Antonio


On Jul 15, 3:02 pm, Jimmy Eng <[email protected]> wrote:
> It's hard to tell from the dialogue whether the timeout is occuring
> during the search phase or during the pepXML conversion, which are two
> different tasks invoked by the GUI.  I want to think it's the latter
> since Antonio mentions that "pepXML conversions apparently have
> completed".  And if this were the case, I'm not sure that Apache time
> out is the culprit since these conversions shouldn't take forever.
> Anyways, that looks like a handy feature for the next GUI release.
>
> Brian Pratt wrote:
> > That can happen on long searches - Apache times out, leaving your session
> > stuck waiting for a message that never arrives.  You can adjust your Apache
> > config for longer timeouts (look through this group's archives for info on
> > that).
>
> > The next TPP GUI release features a button I added for the user to be able
> > to tell the GUI "no really, it's done, let's go look at the results".
>
> > -----Original Message-----
> > From: [email protected]
> > [mailto:[email protected]] On Behalf Of Jimmy Eng
> > Sent: Wednesday, July 15, 2009 10:26 AM
> > To: [email protected]
> > Subject: [spctools-discuss] Re: pepXML
>
> > Antonio,
>
> > Hopefully Luis or someone else more familiar with the GUI will chime in
> > and help you debug why it appears to not recognize that the pepXML
> > conversions apparently have completed but it still thinks they're
> > running.  There are log files somewhere that the GUI looks at that would
> > be the starting point to figuring out your mystery.
>
> > - Jimmy
>
> > Antonio wrote:
> >> Hi Jimmy,
> >> I have donne it from TPP. the program still gets stuck. pepXML files
> >> are created and Sequest serach is performed, but the program reports
> >> that the command is still running.
> >> I might have a problem with the installation. I will have to reinstall/
> >> rebuild the computer.
> >> Antonio
>
> >> On Jul 9, 2:41 pm, Antonio <[email protected]> wrote:
> >>> Ok Jimmy,
> >>> Thank you very much for your help.
> >>> I'll repeat the entire process from TPP and I will let you know the
> >>> result.
> >>> Regards,
> >>> Antonio
>
> >>> On Jul 9, 2:18 pm, Jimmy Eng <[email protected]> wrote:
>
> >>>> I guess the next step is to repeat the pepXML conversion from the GUI
> >>>> and see if the GUI reports that the command completed successfully.  If
> >>>> it does, organize a couple of search directories using the same
> >>>> structure and repeat the pepXML conversion.  Still getting stuck or is
> >>>> the processes reported to be completed?
> >>>> If if looks like the first pepXML file is generated/completed but the
> >>>> interface thinks the command is still running, I'm going to need Luis to
> >>>> chime in on what to look for as I've exhausted the bits I have knowledge
> >>>> of.  So let us know what happens when you try the above.
> >>>> - Jimmy
> >>>> Antonio wrote:
> >>>>> Hi Jimmy,
> >>>>> OK, done it. No problem, the command were successfull, all finished,
> >>>>> th eTPP window indicated that the command was sucessfull and is
> >>>>> finished. i can open the basename.pep on TPP and all seens OK.
> >>>>> What next?
> >>>>> Antonio
> >>>>> On Jul 8, 12:33 pm, Jimmy Eng <[email protected]> wrote:
> >>>>>> Antonio,
> >>>>>> Can you try this.  Replace "basename" with one of your RAW/mzXML file
> >>>>>> base name (i.e. <basename>.mzXML)
> >>>>>> Collate data as
> >>>>>>     c:/Inetpub/wwwroot/ISB/data/AAS/basename.mzXML
> >>>>>>     c:/Inetpub/wwwroot/ISB/data/AAS/basename/  contains dta/out
> >>>>>>     c:/Inetpub/wwwroot/ISB/data/AAS/sequest.params
> >>>>>> Then in a command prompt run
> >>>>>>     cd c:/Inetpub/wwwroot/ISB/data/AAS/
> >>>>>>     Out2XML basename 1
> >>>>>> This should create basename.pep.xml in the AAS directory.  This simple
> >>>>>> exercise is just to confirm that it runs through correctly and the
> >>>>>> process finishes.  The next thing to try is to repeat the above data
> >>>>>> structure but try the pepXML conversion in the GUI.  Hopefully this
> >>>>>> isolates whether you're experiencing a pepXML conversion problem or a
> >>>>>> GUI problem.
> >>>>>> - Jimmy
> >>>>>> Antonio wrote:
> >>>>>>> Hi Jimmy,
> >>>>>>> I run Sequest from Bioworks on our computer cluster, and then
> > transfer
> >>>>>>> the files to the local machine running TPP, so yeas I had the c:/
> >>>>>>> Inetpub/wwwroot/ISB/data/AAS/test/
> >>>>>>> With the out-and dta- files in it.
> >>>>>>> I have attempted to run Sequest from TPP and I had the same problem;
> >>>>>>> the dta and out files are created, but the command indicates that is
> >>>>>>> still running. The problem occurs whether I send a few files or a
> >>>>>>> single one. But I have more than one file on the queue, the command
> >>>>>>> will not proceed to the next file. I can run Sequest from Bioworks on
> >>>>>>> the local machine without any problems.
> >>>>>>> On Jul 2, 6:55 pm, Jimmy Eng <[email protected]> wrote:
> >>>>>>>> Antonio,
> >>>>>>>> That warning about not being able to open the mzXML file is not
> >>>>>>>> indicative of the underlying problem.  It is truly just a warning
> > and
> >>>>>>>> the analysis process is capable of finishing correctly even if the
> >>>>>>>> corresponding mzXML file is missing.
> >>>>>>>> The important question that's not clear from your description below
> > is
> >>>>>>>> how did you run the Sequest search?  Did you run it separately via
> >>>>>>>> Bioworks or did you run the search through the TPP?  Although
> > helpful
> >>>>>>>> but not required, it doesn't seem like you did the latter.  Do you
> > have
> >>>>>>>> a directory (e.g. c:/Inetpub/wwwroot/ISB/data/AAS/test/) that has
> > the
> >>>>>>>> Sequest .out files in it?
> >>>>>>>> - Jimmy
> >>>>>>>> Antonio wrote:
> >>>>>>>>> I have installed TPP v4.2 on windows XP. I have created the mzXML
> >>>>>>>>> datafiles from my Sequest search. Now I'm making the corresponding
> >>>>>>>>> pepXML files. I see that the first file is being created, it seems
> >>>>>>>>> that is finished but I see the following warming message at the end
> > of
> >>>>>>>>> the "Output so far" field:
> >>>>>>>>> warning: cannot open mzXML file "c:/Inetpub/wwwroot/ISB/data/AAS/
> >>>>>>>>> test.mzXML" for reading MS instrument info and scan times.
> >>>>>>>>> And the command status window indicates that the command is still
> >>>>>>>>> running. Is it? I do not see the file increasing in size. I can
> > open
> >>>>>>>>> the pepxml file, although IE indicates that there is an error on
> > page.
> >>>>>>>>> It seems to me that the program is stuck and is not progressing to
> >>>>>>>>> next task: the creation of the next pepXML file. Solutions?
> >>>>>>>>> Thanks,
> >>>>>>>>>  Antonio- Hide quoted text -
> >>>>>>>> - Show quoted text -- Hide quoted text -
> >>>>>> - Show quoted text -- Hide quoted text -
> >>>> - Show quoted text -- Hide quoted text -
> >>> - Show quoted text -

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