Thanks.

I have used TPP before but didn't do any sequest search since I don't have
TPP on the same computer where Bioworks is installed due to some issues.

At the end though I can't bring the pep.XML files to 'Scaffold' which is my
objective.

Tamanna


On Wed, Mar 10, 2010 at 7:08 PM, Darryl Davis <[email protected]> wrote:

> I am attaching a file that has cmd line options for dta to mzXML to .out to
> pepXML (like Bioworks view of results).  This workflow works and I am sure
> someone has a better way of doing it.
> DD
>
>
> On Wed, Mar 10, 2010 at 6:21 PM, Darryl Davis <[email protected]> wrote:
>
>> OK find the same sort of response on my side.  I think it really wants the
>> .raw file around since I can produce .out from .dta as long as .raw file is
>> loaded.  I can then convert this to .srf that has results.  If the .raw file
>> is not there gives error that analysis file does not match results.
>>
>> Good news is the .out files are gd. so maybe now you can use TPP pipeline
>>  .out to pepXML converter (Out2XML).
>>
>> Which leads to "other" tools.  You could take .dta and convert to mzXML
>> using TPP then do your sequest search from there.
>>
>> There are many other tools that have been developed to work w/ dtas
>> themselves but hopefully the above works.
>>
>> I am guessing that you have an .mgf because it isnt a Thermo data run?  If
>> this is the case then ofcourse you could have taken that proprietary format
>> and converted it then ran it through TPP to get Sequest results as well.
>>
>> Good luck,
>> DD
>>
>> On Wed, Mar 10, 2010 at 4:44 PM, Tamanna S Rahman <
>> [email protected]> wrote:
>>
>>> Hi Darryl,
>>>
>>> Thanks for your lead.
>>>
>>> I could run the the search but could not view the search results in
>>> bioworks. After converting the DTA and OUT files to SRF  I could open the
>>> search results but found no hits listed eventhough some of the OUT files has
>>> peptides identified
>>>
>>> Then I brought the DTA and OUT (as well as SRF separately) files to
>>> scaffold and Theres turned out to be no results either.
>>> Any idea why it could happen??
>>>
>>> Also what are the other tools for sequest search using MGF, DTA  etc.??
>>>
>>> Thanks
>>> Tamanna
>>>
>>>
>>>  On Wed, Mar 10, 2010 at 12:14 PM, Darryl Davis <[email protected]>wrote:
>>>
>>>>  For dta work try Actions- Sequest search.  Choose folders w/ DTAs
>>>> deselect use SRF file.  Deselect dta generation.  Choose sequest.params 
>>>> file
>>>> and then start search.
>>>>
>>>> If you have mgf or dta format already there are other tools than
>>>> Bioworks to use (ofcourse I state the obvious).
>>>> DD
>>>>
>>>>
>>>> On Wed, Mar 10, 2010 at 11:54 AM, Tamanna Sultana <
>>>> [email protected]> wrote:
>>>>
>>>>> Does anyone knows a way of importing MGF or DTA files to Bioworks for
>>>>> a Sequest search?
>>>>>
>>>>> I have a dataset in *.mgf format and I would like to do a Sequest
>>>>> search.
>>>>>
>>>>> 1. I could not import mgf to bioworks. I know that sequest uses *.dta
>>>>> file for search, so I converted the mgf to dta but failed to import
>>>>> the dta to bioworks. Bioworks seem to accept *.RAW only.
>>>>>
>>>>> 2. I saw under tools in 'Bioworks' I could import spectral data in
>>>>> mzdata format, that did not work either.
>>>>>
>>>>> Anyone have any suggestion??
>>>>> Thanks
>>>>> Tamanna
>>>>>
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