Jimmy,

I am using the Mascot2XML from the last TPP version released
9-9-2009.  Can you please point me to the trunk where I can download
rev 4945 from your April 15, 2010 check-in?

thanks

Ron

On Jun 30, 7:02 pm, Jimmy Eng <[email protected]> wrote:
> I have faint memories of dealing with this but I'm away from work so
> can't confirm.  This might've been fixed in rev 4945 check-in on April
> 15th; my check-in log message for Mascot2XML was "parsing update for
> entry with protein n-term modification which doesn't seem to be
> handled by current code".
>
> Are you able to compile Mascot2XML from trunk and see if the problem
> goes away?  Otherwise, I'll follow-up with this next week when I'm
> back at work.
>
> On Tue, Jun 29, 2010 at 5:59 AM, Ronald W. Finnegan <[email protected]> wrote:
>
>
>
> > Can anyone tell me if this bug reported back in April 2009 has been
> > fixed:
>
> > Thermo Orbitrap RAW file is inputted into tpp -> convert to mzxml ->
> > convert to mgf -> run mascot -> convert to pepXML
>
> > The problem is as follows:
>
> > When I use the mascot default modification Acetyl (protein N-term),
> > the TPP converter that converts the mascot output .DAT file to pepXML
> > format creates the following header in the pepXML file:
>
> > <aminoacid_modification aminoacid=" " mass="42.010559"
> > massdiff="42.010559" peptide_terminus="n" variable="Y"/>
> > <aminoacid_modification aminoacid="N" mass="156.053486"
> > massdiff="42.010559" peptide_terminus="n" variable="Y"/>
> > <aminoacid_modification aminoacid="-" mass="42.010559"
> > massdiff="42.010559" peptide_terminus="n" variable="Y"/>
> > <aminoacid_modification aminoacid="t" mass="42.010559"
> > massdiff="42.010559" peptide_terminus="n" variable="Y"/>
> > <aminoacid_modification aminoacid="e" mass="42.010559"
> > massdiff="42.010559" peptide_terminus="n" variable="Y"/>
> > <aminoacid_modification aminoacid="r" mass="42.010559"
> > massdiff="42.010559" peptide_terminus="n" variable="Y"/>
> > <aminoacid_modification aminoacid="m" mass="42.010559"
> > massdiff="42.010559" peptide_terminus="n" variable="Y"/>
>
> > If you look at this header closely, the entries are not only
> > meaningless, but there is something funny to be seen if you look at
> > the aminoacid="" entries:
>
> > aminoacid=" "
> > aminoacid="N"
> > aminoacid="-"
> > aminoacid="t"           =  N - term
> > aminoacid="e"
> > aminoacid="r"
> > aminoacid="m"
>
> > as far as I know the aminoacid property should indicate aminoacid
> > letters and not be spelling out N-term. This is obviously a parsing
> > error occurring somewhere during the conversion.
>
> > Here is the link the original thread:
>
> >http://groups.google.com/group/spctools-discuss/browse_thread/thread/...
>
> > thanks
>
> > Ron
>
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