Hi,
Although Thermo people told me otherwise Xcalibur works fine under win
7-64 bit. so I managed to convert the.raw files to mzxml format and I
tried to run a sequest search using the params file from bioworks that
I dont have any access right now. TPP(4.4) is looking for sequest
under bioworks folder (which I dont have on this computer)


 run_in c:/Inetpub/wwwroot/ISB/data/020711_crudeLYSATE_HPRP_SIDL; c:
\Inetpub\tpp-bin\runsearch -pc:/Inetpub/wwwroot/ISB/data/parameters/
ipi_mouse.params -P15 020711_crudeLYSATE_1to1_10percentACN_1_H.mzXML

 RUNSEARCH
 Written by J.Eng (c) 2000
 TPP v4.4 VUVUZELA rev 1, Build 201010121551 (MinGW)

 Cannot find Sequest executable in c:\xcalibur\system\programs
\bioworksbrowser\.
command "c:\Inetpub\tpp-bin\runsearch -pc:/Inetpub/wwwroot/ISB/data/
parameters/ipi_mouse.params -P15
020711_crudeLYSATE_1to1_10percentACN_1_H.mzXML" failed: Operation not
permitted

Command FAILED

is there any easy fix for this? or are you thinking about adding
proteome discoverer -sequest route to the next version of TPP?
thank you
g crynen

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