Hi Matt,

Is it possible to turn off the decoy altogether in the search when
there are decoy in the database?  I tried a search with DecoyPrefix =
"".  Would that have the desired effect?

Thanks,
-David

On Fri, Mar 11, 2011 at 6:52 AM, Matthew Chambers
<[email protected]> wrote:
> 1. Yes. Set the DecoyPrefix parameter to whatever your existing decoys use.
> 2. Interesting question, since ProteinProspector's new pepXML export is not
> really flexible about how the decoys are indicated (it's always with a short
> '-' prefix and the decoy protein accessions are always trimmed so that
> "sp|P00001|BLAHBLAH" becomes "P00001").
>
> -Matt
>
>
> On 3/11/2011 6:15 AM, Ben Collins wrote:
>>
>> Hi,
>>
>> I'm trying to use myrimatch as one of a number of search engines to
>> combine later with iprophet. It seems that later versions of myrimatch
>> are doing on the fly decoy database generation, because I tried to
>> search a database that already had decoys appended and ended up
>> doubling up on the decoys. So my questions are:
>>
>> 1. Is it possible to switch of the on-the-fly decoy database
>> generation in myrimatch so I can use a single database with decoys
>> already appended for all search engines?
>>
>> 2. If its not possible to change the myrimatch decoy behaviour, will
>> iprophet tolerate results from different search engines using non-
>> identical databases?
>>
>> Many thanks for any advice,
>> Ben
>>
>
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