I also use AsapRatio and I frequently have NAs in my results and as you sad 
I am wondering of it is an experimental problem. Does anyone have 
experienced this problem before? What should I do to avoid it?
 
regards,
 
Julia
 

Em quinta-feira, 26 de julho de 2012 14h58min44s UTC-3, Daniel FS escreveu:

> I'm using TPP v4.4 vuvuzela rev 1 and I'm working with SILAC cells. 
> Everything is going right until the quantification time, when my result 
> seems to be very bad. After 8 runs with different proportions of 
> heavy/light cells (1:1, 2:1) in a following conditions (Thermo Orbitrap -> 
> Mascot Search with Fixed Mod. on Carbamidomethyl and Variable Mod. on 
> Label(6)K and Oxidation(M)  -> Analysis Pipeline with XPRESS mass diference 
> (K) 6.02 and ASAPRatio with change label K and Specific mass residue K 
> 134.114), my results are around 70% N_A, and just 20% really quantified. My 
> question is: why there is so much N_A in my results? I know that N_A is 
> something about cannot quantify, but what it is exactly? Is it something 
> experimental or is it a bad use of TPP?
>
> Thanks in advance,
>
> Daniel
>

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