Hi Erik,
I have no experience with Cent OS, but maybe this can help you:
http://tools.proteomecenter.org/wiki/index.php?title=TPP:Installing_the_Trans-Proteomic_Pipeline_%28TPP%29_4.4.0_on_Mac_OS_X_10.6.4
The page above describes how I installed the TPP on my Mac and contains the 
changes I made to the the apache2 config file. I hope it also contains the 
answer to your problems...

Cheers,
Bjorn 

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