Hi Rebekah, The goal of the model is to capture the peptide property of containing N-glyco motif Nx(S/T) or not. Since in a glyco capture experiment correct identifications will tend to be enriched for peptides containing the motif this model will usually tend to boost the probabilities of those peptides containing the motif and reduce the probabilities of those not containing the motif. The actual amount of adjustment is learned from the data and is therefore dataset dependent but can be looked up by clicking on any PeptideProphet probability link.
Cheers, -David On Tue, Apr 29, 2014 at 7:28 PM, Ruby <[email protected]> wrote: > Hi- > Where can I find a description of what the N-glyco model in the TPP does? > I need to include a short description for a manuscript as to unique > features of TPP - does it actually re-weight the peptides that contain the > motif if a deamidation found at N? > > Thanks! > Rebekah > > -- > You received this message because you are subscribed to the Google Groups > "spctools-discuss" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > To post to this group, send email to [email protected]. > Visit this group at http://groups.google.com/group/spctools-discuss. > For more options, visit https://groups.google.com/d/optout. > -- You received this message because you are subscribed to the Google Groups "spctools-discuss" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. To post to this group, send email to [email protected]. Visit this group at http://groups.google.com/group/spctools-discuss. For more options, visit https://groups.google.com/d/optout.
