Dear Fred, Every time you add a variable modification the algorithm has to evaluate an order-of-magnitude more possibilities. Thus, you should use static mods as much as possible or try to limit your search space in other ways (e.g. use a more narrow mass tolerance).
-David On Mon, Oct 20, 2014 at 6:42 AM, DELOLME Frederic <[email protected]> wrote: > Hello TPP team, > > At this time, I'm using TPP for iTRAQ quantitation after a search with > X!Tandem. > > I'm facing some problems with the duration of the search. In my case, I use > 1 static modification and I'd like to include seven others potential > modifications. > With only one static and one or two potential, it's quite faste (around > 20-30 min on my system 2 processors, 8 virtual cores). As soon as I increase > the number of potential modif the duration increase dramatically. Did you > observe such issue ? If not, do you use a refinement search ? > > I'm wondering if it's only a matter of power of my computer or if it's > rather due to X!Tandem algorithm. > > Thanks in advance for any advice. > > Fred > > -- > You received this message because you are subscribed to the Google Groups > "spctools-discuss" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > To post to this group, send email to [email protected]. > Visit this group at http://groups.google.com/group/spctools-discuss. > For more options, visit https://groups.google.com/d/optout. -- You received this message because you are subscribed to the Google Groups "spctools-discuss" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. To post to this group, send email to [email protected]. Visit this group at http://groups.google.com/group/spctools-discuss. For more options, visit https://groups.google.com/d/optout.
