Hi Peter, 

I also have problem with proteinprophet. After fail to generate iprophet in 
TPP4.7 & 4.8. I switch to TPP 4.6 now. I tried to merge 12 iprophet files 
(each file is 1-2 GB). But proteinprophet throw out a problem after reading 
in 10 files. Something like, "The application has terminate in an unusually 
way, please contact the administrator..." But when I try on 8 files only, I 
still got the same error.

How big is your file? 
Rachel

On Thursday, September 10, 2015 at 1:41:35 PM UTC+8, [email protected] wrote:
>
> Hi,
>
>
> I'm trying to generate a prot.xml file from 120 interact.ipro.pep.xml 
> files. There seems to be some numerical limit on ProteinProphet as when I 
> try to add all the ipro files the system immediately returns an error 256 
> code. If I choose a smaller number, say 10 ipro files, it goes to 
> completion. Is there some max number of files that can be combined with 
> ProteinProphet? Is there some way around this? It's an absolute requirement 
> for me to make a prot.xml file from this data.
>
>
> I'm using TPP v 4.8.0 on aWin7 system, 64-bit, 64 GB RAM.
>
>
> If this is a known problem, I guess I could just pool more pep.xml files 
> into each ipro file to reduce my overall number of files input into 
> ProteinProphet. I've got some very large interact.ipro.pep.xml that are 
> taking time to process into the prot.xml but that's to be expected.
>
>
> Thanks,
>
>
> Peter
>

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