Eslam,

Setting "num_threads = 0" is the best you can do.  There's no free lunch
... a database that's 100 times larger than the human UniProt fasta will
take approximately 100 times longer to run, e.g. a 10 minute human search
would translate to a 17 hour search if the database were 100 times larger.
You can give things up (no variable modifications, no missed cleavages,
narrow precursor mass tolerance, etc.) to hopefully speed things up a
little bit.  Otherwise you just have to throw more horsepower at it.  You
can get Broadwell-class Xeon processors with up to 24 cores in them.

On Tue, Aug 9, 2016 at 11:30 PM, Eslam Nouri <eslamno...@gmail.com> wrote:

> Hi Eric,
>
> I am using comet. In my comet file the number of threads is equal to zero 
> "num_threads
> = 0". I have attached my system information. Is there any way to increase
> the data analysis time by defining a thread number?
>
> Thanks, Eslam
>
> On Tue, Aug 9, 2016 at 11:18 PM, Eric Deutsch <edeut...@systemsbiology.org
> > wrote:
>
>> Which search engine are you using? Comet? Tandem?
>>
>>
>>
>> Comet has num_threads:
>>
>> http://comet-ms.sourceforge.net/parameters/parameters_201601
>> /num_threads.php
>>
>>
>>
>> Tandem has threads:
>>
>> http://www.thegpm.org/TANDEM/api/st.html
>>
>>
>>
>>
>>
>>
>>
>> *From:* spctools-discuss@googlegroups.com [mailto:spctools-discuss@googl
>> egroups.com] *On Behalf Of *Eslam Nouri
>> *Sent:* Tuesday, August 9, 2016 11:05 PM
>> *To:* spctools-discuss@googlegroups.com
>> *Subject:* [spctools-discuss] Multi core analysis
>>
>>
>>
>> Hello_
>>
>>
>>
>> I am using TPP for the database search of microbiome proteins. Since the
>> fasta file that I have is more than 100 times larger than human uniprot
>> fasta file, the database search for a single DDA run takes more than 12
>> hours. Is there any way to have faster analysis using multi-cores?
>>
>>
>>
>> Thanks, Eslam
>>
>> Proteomics core facility
>>
>> University of southern California
>>
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