Hello Francesca,
It looks like this is a problem with Comet trying to produce .out files as
output; we will contact the developers to troubleshoot this.

You may want, however, to produce pepXML output, which is the format used
by TPP (assuming that's your desired workflow) -- please mind the following
parameters in your file and change them accordingly:

output_pepxmlfile = 0
output_outfiles = 1

Cheers,
--Luis



On Thu, Feb 2, 2017 at 1:24 PM, Francesca Barry <[email protected]
> wrote:

> Hello,
>
> I'm trying to run a Comet search in TPP against a human database.
> Ultimately, I'm trying to run the decoy search, which didn't work.
>
> Since this didn't work, I went back and tried to re-run the forward search
> that I did 3 weeks ago with the exact same .mzML file, the exact same
> .params file, and the exact same fasta sequence as before (which all worked
> previously).  Now for some reason this forward/non-decoy search doesn't
> even work and gives the same error as I'm getting when trying to do the
> decoy search (see attached image, which is the error for decoy search, but
> it's the same error either way).
>
> I have also attached the params file that I used 2 weeks ago (which I only
> modified this time by setting the decoy search = 1).
>
> Any help would be appreciated because I don't understand how it no longer
> works with the EXACT same files when it worked 3 weeks ago.
>
> Thank you!
>
> Francesca
>
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