Thanks for reply, Alexey. I am using the latest version, and I've posted my 
question on git.https://github.com/chhh/MSFragger-GUI/issues/63

David

On Tuesday, May 22, 2018 at 12:56:51 PM UTC-7, Alexey Nesvizhskii wrote:
>
> David,
>
> We have done many comparisons. You should be getting very similar results 
> when performing closed searches.
> You can post questions on MSFragger here:
> https://github.com/chhh/MSFragger-GUI/issues
>
> Also, are you using the latest version? 
> You can get the latest version of MSFragger here:
> http://msfragger.arsci.com/upgrader/
>
> Best,
> Alexey Nesvizhskii
>
> On Tuesday, May 22, 2018 at 12:40:51 PM UTC-4, David Zhao wrote:
>>
>> Hi there,
>>
>> We've started to evaluate MsFragger tool, has anybody done a comparison 
>> between Comet and MsFragger? Is it complementary to Comet? We've run a 
>> couple of MsFragger searches, using parameters converted from comet 
>> parameters, it seems MsFragger is focusing more on finding more PTMs, which 
>> results in many long peptide hits, and overriding charge option doesn't 
>> seem to be working...
>>
>> Any inputs or comments is greatly appreciated!
>> Thanks,
>>
>> David
>>
>

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