I have recently started playing with proteomics data and I have pretty much the same question as Volkix (although I haven't reached the StPeter step yet)!
So what is the main difference between Comet and Xtandem? For example, is one better-suited for particular data than the other? As Volkix also mentioned, perhaps their most obvious difference is that Comet is much faster than Xtandem. How is this explained? Does it have a consequence on the quality of the results? I read in a tutorial TPP paper (Deutsch et al. 2010; Proteomics) that the pepXML results from multiple search engines can be combined together. So is combining different search engines something people usually do? If it is, what other search engines are usually used? The paper refers to SpectraST, but since 8 years have passed since it was published, I'm wondering if there have been any changes lately... Thanks, Panos On Sunday, 25 March 2018 19:00:39 UTC+3, Jason Winget wrote: > > Any search engine should work, as long as you can generate a valid ProtXML > file as input to StPeter -- You received this message because you are subscribed to the Google Groups "spctools-discuss" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. To post to this group, send email to [email protected]. Visit this group at https://groups.google.com/group/spctools-discuss. For more options, visit https://groups.google.com/d/optout.
