Hi,
I tried to analyze my DSS and DMTMM cross-linking data using  Kojak and 
PeptideProphet.
Kojak run properly, however Peptideprophet claims for Trypsin GluC 
digestion, which is not defined. Kojak could handle it.
Why does PeptideProphet need the enzyme info at all?

Is this possible to define for PeptideProphet the TryGluC "enzyme"? i could 
not find it in the 
I read in the bioRxiv Mendes et al publication 'An integrated workflow for 
cross-linking/mass spectrometry" , that ".....we and the developers of 
these tools could not pair Kojak with PeptideProphet for sequential 
digestion."

Thanks for answers in advance.

best

Zsuzsi

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