Hi Mike,

many thanks for your prompt answer. I tried and indeed if I defined my 
sequential digest  in Kojak as you suggeste as "trypsin_gluc", then the 
PeptideProphet can analyze the pep.xml file. Many thanks.

Zsuzsi

Am Mittwoch, 11. September 2019 01:57:20 UTC+2 schrieb Michael Hoopmann:
>
> Hi Zsuzsi,
> Could you try renaming your enzyme, "trypsin_gluc" ?  I think that is the 
> secret enzyme name that PeptideProphet recognizes for that enzyme 
> combination. Sorry for the trouble, I'll have dig through the code to see 
> who is at fault (Kojak or PeptideProphet) for not properly interpreting the 
> enzyme combination.
>
> As for the bioRxiv publication, I'm not sure if anyone on that author list 
> tried to contact us, so it seems there is an error or exaggeration in that 
> statement... We appreciate you made the effort.
>
> Cheers,
> Mike
>
> On Tue, Sep 10, 2019 at 7:30 AM nzsuzsanna <[email protected] 
> <javascript:>> wrote:
>
>> Hi,
>> I tried to analyze my DSS and DMTMM cross-linking data using  Kojak and 
>> PeptideProphet.
>> Kojak run properly, however Peptideprophet claims for Trypsin GluC 
>> digestion, which is not defined. Kojak could handle it.
>> Why does PeptideProphet need the enzyme info at all?
>>
>> Is this possible to define for PeptideProphet the TryGluC "enzyme"? i 
>> could not find it in the 
>> I read in the bioRxiv Mendes et al publication 'An integrated workflow 
>> for cross-linking/mass spectrometry" , that ".....we and the developers of 
>> these tools could not pair Kojak with PeptideProphet for sequential 
>> digestion."
>>
>> Thanks for answers in advance.
>>
>> best
>>
>> Zsuzsi
>>
>> -- 
>> You received this message because you are subscribed to the Google Groups 
>> "spctools-discuss" group.
>> To unsubscribe from this group and stop receiving emails from it, send an 
>> email to [email protected] <javascript:>.
>> To view this discussion on the web visit 
>> https://groups.google.com/d/msgid/spctools-discuss/b99a0ebf-2552-4622-ad8b-68d92f91fac7%40googlegroups.com
>>  
>> <https://groups.google.com/d/msgid/spctools-discuss/b99a0ebf-2552-4622-ad8b-68d92f91fac7%40googlegroups.com?utm_medium=email&utm_source=footer>
>> .
>>
>

-- 
You received this message because you are subscribed to the Google Groups 
"spctools-discuss" group.
To unsubscribe from this group and stop receiving emails from it, send an email 
to [email protected].
To view this discussion on the web visit 
https://groups.google.com/d/msgid/spctools-discuss/3f98271f-f03b-4e31-9068-64622f9ec4d2%40googlegroups.com.

Reply via email to