"unable to open database file" errors are usually caused by incorrect file protection settings or directory protection settings, but I don't think this one is.
This is a 5.0G database with one table that I created in Windows 7 64-bit with sqlite3 3.7.16.2 from Perl. I can connect to the DB, read from the db, write to the db, and retrieve back what I wrote to it, but I can't create an index on it. I was able to create an index on it by copying it to a Linux system and creating the index there. I have write permission on the directory. (You can never be sure, with the madness of the Windows 7 file security and read-only settings, but I am able to create and index other databases in the same directory in the same way when they are not so large.) $ ls -l gi2taxonNt -rwxrwxrwx+ 1 phil None 5.0G Jun 4 11:01 gi2taxonNt $ sqlite3.exe gi2taxonNt SQLite version 3.7.16.2 2013-04-12 11:52:43 ... sqlite> .schema CREATE TABLE taxon (gi INTEGER, taxon INTEGER); sqlite> insert into taxon (gi, taxon) VALUES (1, 1); sqlite> select * from taxon where gi=1; [very long wait...] 1|1 sqlite> create index taxon_gi_index on taxon(gi); Error: unable to open database file Same error if I make the CREATE INDEX call thru the Perl DBI. Any idea what causes this error? Is it caused by using a 32-bit sqlite3? How does a 32-bit app access a 5G file? Is there a 64-bit Windows or Linux SQLite available? _______________________________________________ sqlite-users mailing list sqlite-users@sqlite.org http://sqlite.org:8080/cgi-bin/mailman/listinfo/sqlite-users