http://www.gmwatch.org/print-archive2.asp?arcid=6668

GM is obsolete - non-GM biotech now "the first choice" (21/6/2006)

The Foundation on Economic Trends (FET), founded by the economist 
Jeremy Rifkin, who has highlighted the dangers of genetic engineering 
since the early 1980s, has recently completed a white paper on the 
next generation of biotech agriculture, called Marker Assisted 
Selection (MAS).

Rifkin, like many others, is convinced that MAS has eclipsed genetic 
engineering in its potential and that GE is a failed technology whose 
limitations are hotly denied by corporate-friendly scientists and the 
entrenched interests they represent.

Rifkin's FET sees its position paper as "opening up a new 
conversation in the debate surrounding GM food." Those boiotech 
proponents wedded to an already outmoded vision of the future of 
agriculture, centered on GE and patents, can be relied upon to do 
their damndest to try and drown out that conversation.

EXCERPTS: ...new cutting edge technologies have made gene splicing 
and transgenic crops obsolete and a serious impediment to scientific 
progress. The new frontier is called genomics and the new 
agricultural technology is called Marker Assisted Selection, or MAS.

Wally Beversdorf, former vice president of plant science research at 
Syngenta, candidly admitted that although the company was still 
engaged in GM technology, "marker assisted selection is the first 
choice" now in the company's research priorities.

European Environmental Commissioner Stavros Dimas raised the question 
of [GM] contamination of plant varieties and loss of biodiversity in 
a speech to environmental ministers of the 25 EU member states on 
April 5, 2006. Dimas told his colleagues that "GMO products raise a 
whole new series of possible risks to the environment, notably 
potential long term effects that could impact on biodiversity." Dimas 
said he was particularly concerned about loss of biodiversity because 
of the vast potential afforded by the new MAS technology... Dimas 
noted that "MAS technology is attracting considerable attention" and 
said that the European Union "should not ignore the use of 'upgraded' 
conventional varieties as an alternative to GM crops".
---

http://www.foet.org/FETSupportStatementonMAS.pdf

The Foundation on Economic Trends (FET) Statement of Support for 
Genomics Research and Marker Assisted Selection Technology within the 
Context of a Broader, More Holistic, Agroecological Approach to 
Farming

For years, the life science companies - Monsanto, Syngenta, Bayer, 
Pioneer, etc. - have argued that GM food is the next great scientific 
and technological revolution in agriculture, and the only efficient 
and cheap way to feed a growing population in a shrinking world. 
Non-governmental organizations (NGOs), including my own, The 
Foundation on Economic Trends, have been cast as the villains in this 
unfolding agricultural drama, and often categorized as modern 
versions of the English Luddites, accused of continually blocking 
scientific and technological progress because of their opposition to 
GM food.

Now, new cutting edge technologies have made gene splicing and 
transgenic crops obsolete and a serious impediment to scientific 
progress. The new frontier is called genomics and the new 
agricultural technology is called Marker Assisted Selection, or MAS. 
The new technology offers a sophisticated, new method to greatly 
accelerate classical breeding. A growing number of scientists believe 
that MAS - which is already being introduced into the market - will 
eventually replace GM food.

Scientists are mapping and sequencing the genomes of major crop 
species and using the findings to create a new approach to advancing 
agricultural technology. Instead of using molecular splicing 
techniques to transfer a gene from an unrelated species into the 
genome of a food crop to increase yield, resist pests, or improve 
nutrition, scientists are now using Marker Assisted Selection to 
locate desired traits in other varieties or, wild relatives of a 
particular food crop, then cross breeding those plants with the 
existing commercial varieties to improve the crop. With MAS, the 
breeding of new varieties always remain within a species, thus, 
greatly reducing the risk of environmental harm and potential adverse 
health effects associated with GM crops. Rapidly accumulating 
information about crop genomes is allowing scientists to identify 
genes associated with traits like yield and then scan crop relatives 
for the presence of those genes. Using MAS, researchers can upgrade 
classical breeding and reduce by 50% or more the time needed to 
develop new plant varieties by pinpointing appropriate plant partners 
at the gamete or seedling stage.

An increasing number of researchers around the world in academic, 
government, and commercial laboratories are switching to MAS as an 
alternative to gene splicing technology in the development and 
enhancement of existing food crops. Using MAS, researchers in the 
Netherlands have developed a new lettuce variety resistant to an 
aphid that causes reduced and abnormal growth in lettuce fields in 
California and Europe. Researchers at the US Department of 
Agriculture have used MAS to develop a strain of rice that is soft on 
the outside but remains firm on the inside after processing. 
Scientists in the UK and India have used MAS to develop pearl millet 
that is tolerant of drought and resistant to mildew. The crop was 
introduced into the market in India in 2005. Even Syngenta, one of 
the world's leading agribusiness companies, has begun to turn its 
attention away from GM and toward MAS. Syngenta researchers have 
developed a wheat variety with increased resistance to Fusarium 
blight.

Wally Beversdorf, former vice president of plant science research at 
Syngenta, candidly admitted that although the company was still 
engaged in GM technology, "marker assisted selection is the first 
choice" now in the company's research priorities. Pioneer Hi-Bred 
International, a subsidiary of Dupont, is using MAS to develop new 
soybean varieties with enhanced disease and pest tolerance. John 
Soper, director of soybean research at the company says, "We have 
seen only the tip of the iceberg when it comes to the benefits MAS 
technologies will provide".

While MAS is emerging as a promising new agricultural technology with 
broad application, the limits of transgenic technology are becoming 
increasingly apparent. Most of the transgenic crops introduced into 
the fields express only two traits, resistance to pests and 
compatibility with herbicides and rely on the expression of a single 
gene - hardly the sweeping agricultural revolution touted by the life 
science companies at the beginning of the GMO era.

MAS is in the early stages of development but has vast potential as 
an alternative to genetically modified crops using gene splicing 
within and between species. Of course, researchers emphasize that 
there is still much work to be done in understanding the 
choreography, for example, between single genetic markers and complex 
genetic clusters and environmental factors, all of which interact to 
affect the development of the plant.

Until genetic engineers overcome the barriers to working with groups 
of genes, they are not going to get far on the traits like intrinsic 
yield and drought tolerance that really matter in agriculture. 
Genomics research is steadily moving into this more promising arena 
of research and development, opening up the prospect of new ways of 
thinking about the relationship between genotype and phenotype and 
environmental context. Organic farmers and processors are 
particularly keen on MAS because of its potential to radically reduce 
the costs of bringing organic produce to market.

While MAS has great potential, a word of caution is in order. It 
should be noted that MAS is of value to the extent that it is used as 
part of broader, agroecological approach to farming, that integrates 
new crop introductions with a proper regard for all of the other 
environmental, economic, and social factors that together determine 
the sustainability of farming.

The wrinkle is that the continued introduction of GM crops could 
contaminate existing plant varieties, making the new MAS technology 
more difficult to use. Cleaning up contaminated genetic programs 
could prove to be as troublesome and expensive in the future as 
cleaning up viruses that currently invade software programs. Cross 
contamination of non-GMO and organic crops with GMOs is occurring in 
regions where large swaths of farmland have been planted with GMO 
crops. The danger is that conventional plant varieties and wild 
relatives of all major crop varieties will be contaminated with 
spliced genetic material from GM crops. In the US, where so much 
farmland is already planted with GM crops, the contamination is now 
widespread, threatening both conventional and organic food crops.

A landmark 2004 survey conducted by the Union of Concerned 
Scientists, found that non-GM seeds from three of America's major 
agricultural crops -corn, soybeans, and canola - were already 
"pervasively contaminated with low levels of DNA sequences 
originating in genetically engineered varieties of these crops". This 
sobering report concluded that "heedlessly allowing the contamination 
of traditional plant varieties with genetically engineered sequences 
amounts to a huge wager on our ability to understand a complicated 
technology that manipulates life at the elemental level". The authors 
of the study warn that "unless some part of our seed supply is 
preserved, free of genetically engineered sequences, our ability to 
change course if genetic engineering goes awry will be severely 
hampered".

Even the US Biotech Industry Association - BIO -now acknowledges that 
there is widespread GM contamination of a number of American food 
crops, dispelling the myth that GMO can coexist with conventional and 
organic food crops. There is no procedure that will prevent pollen 
flow across fields. The result is that the American government is 
engaged in discussion about how much GMO cross-contamination is 
acceptable to still certify as non-GMO .

European Environmental Commissioner Stavros Dimas raised the question 
of contamination of plant varieties and loss of biodiversity in a 
speech to environmental ministers of the 25 EU member states on April 
5, 2006. Dimas told his colleagues that "GMO products raise a whole 
new series of possible risks to the environment, notably potential 
long term effects that could impact on biodiversity." Dimas said he 
was particularly concerned about loss of biodiversity because of the 
vast potential afforded by the new MAS technology. MAS relies on 
preserving heirloom varieties and landraces and protecting wild 
relatives of food crops to ensure that a diverse pool of valuable 
traits is available to crop breeders. Dimas noted that "MAS 
technology is attracting considerable attention" and said that the 
European Union "should not ignore the use of 'upgraded' conventional 
varieties as an alternative to GM crops".

Equally important, as MAS technology becomes cheaper and easier to 
use, and as knowledge in genomics becomes more dispersed and easily 
available over the next decade, plant breeders around the world will 
be able to exchange information about "best practices" and 
democratize the technology. Already, plant breeders are talking about 
"open source" genomics, envisioning the sharing of genes just as 
Linux and other open source IT organizations currently share software.

The struggle between a younger generation of sustainable agriculture 
enthusiasts anxious to share genetic information and entrenched 
company scientists determined to maintain control over the world's 
seed stocks through patent protection, is likely to be hard fought, 
especially in the developing world.

Given these rapid new developments in genomics research, the prudent 
course of action now is to put GM food and feed crops on hold around 
the world, pending a thorough review of the recent breakthroughs in 
MAS technology. Governments need to solicit studies, hold hearings, 
and evaluate the potential negative impacts that widespread GM 
plantings might have on crippling the prospects for introducing the 
next generation of MAS biotech food crops.

If ever there was an appropriate moment to invoke the "precautionary 
principle" in agriculture, it is now. Introducing an out of date GMO 
technology could seriously undermine the vast possibilities that the 
new MAS technology holds for the future of agriculture around the 
world. If properly used as part of a much larger systemic and 
holistic approach to sustainable agricultural development, MAS 
technology could be the right technology at the right time in history.

Dr. Robert Goodman, dean of Cook College of Rutgers University, and 
formerly head of research at Calgene, a small biotech company that 
introduced the world's first GM food crop, the infamous Flavr-Savr 
tomato - the product failed in the market - summed up the great 
transition now taking place in agricultural biotechnology. Several 
years ago, Goodman, in an extraordinary change of mind, said "from a 
scientific perspective, the public argument about genetically 
modified organisms, I think, will soon be a thing of the pastĀŠ The 
science has moved on, and we're now in the genomics era".

FET supports a rapid development of genomics research and the 
increasing use of Marker Assisted Selection to accelerate classical 
breeding and usher in a new era of sustainable and organic 
agriculture. FET calls for the establishment of a global MAS network 
made up of governments, agricultural research institutions, and farm 
organizations to advance the research and development of MAS 
technology, as part of a more integrated approach to sustainable 
agricultural practices in the 21st century.

FET calls upon the governments of the world, the life sciences 
industry, farmers organizations, food processors, distributors, and 
retailers to benchmark a reasonable phase-out of all existing GM 
crops, in order to reduce the risk of contamination of seed varieties 
whose traits might prove beneficial in MAS development.

FET further calls on governments to enact and enforce strict 
liability laws to hold life science companies financially accountable 
for cross- contamination that adversely affects non-GM farmers, 
gardeners, and consumers.

FET calls on government to break the monopoly that a handful of 
global life science companies enjoy over the world's seed stocks, end 
patent protection on seed varieties and traits, and open the way to 
"open source" access to, and sharing of, genetic information and MAS 
seed varieties to promote cooperative MAS programs and best practices 
around the world.

FET calls on government and civil society to establish and fund more 
extensive programs designed to preserve agricultural biodiversity, 
including the expansion of existing seed banks and the creation of 
new facilities, to ensure the availability of a rich pool of traits 
for use in MAS research and development.


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