Dow to sue over Quebec pesticide  ban 
 
Claiming **no scientific basis** for residential ban, U.S.  company demands 
$2-million (U.S.) in damages under NAFTA's Chapter 11 

MARTIN MITTELSTAEDT 
Globe and Mail update 
April 9, 2009 at 6:44 PM EDT 
_http://www.theglobeandmail.com/servlet/story/RTGAM.20090409.wdow0409/BNStor
y/National/home_ 
(http://www.theglobeandmail.com/servlet/story/RTGAM.20090409.wdow0409/BNStory/National/home)
  
 
Dow AgroSciences LLC has decided to sue the federal government  over 
Quebec's ban on the residential use of pesticides. 

The U.S.-based company, maker of the herbicide 2,4-D, is  claiming 
$2-million (U.S.) in damages, using controversial provisions in the  North 
American 
Free Trade Agreement that allow businesses to sue governments  over 
regulations that harm their interests. 

Although Dow announced last year that it was mulling over  such legal 
action, the company had until this month to file a formal notice of  
arbitration 
under NAFTA and begin its lawsuit. 

The case has attracted wide interest because so-called  cosmetic pesticide 
bans are becoming increasingly popular, with Ontario recently  following 
Quebec's lead in introducing one and many retailers removing chemical  bug and 
weed killers from their shelves. 

Some environmental groups have been pointing to the  possibility that Dow 
would launch its legal action as a reason for renegotiating  the Chapter 11 
provisions in NAFTA that allow investors to seek compensation  over 
government regulations. 

But Dow said in its notice of arbitration, which has been  posted on the 
Foreign Affairs and International Trade website, that its dispute  has arisen 
because Quebec has “no scientific basis to impose the ban.” 

It says 2,4-D, a weed killer often used on dandelions, has  received 
extensive testing and there is **no evidence** it poses a **health or  safety 
risk 
to humans when used according to label directions.** 

Under NAFTA, Dow is required to challenge Ottawa, even  though its problem 
is with a Quebec law. 

Health Canada, which regulates pesticides, has approved  2,4-D for use on 
residential lawns, and ironically, Dow is using the federal  stamp of 
approval as part of the basis of its claim. 

A spokesperson for the company said its action wasn't  taken to try to stop 
pesticide bans from spreading. 

**What is really important here is the scientific  principle. Do we want 
regulations in Canada made on political whim or do we want  them based on 
science?** said Brenda Harris, regulator and government affairs  manager for 
Dow 
AgroSciences Canada Inc. 

But Lisa Gue, a spokesperson for the David Suzuki  Foundation, said she was 
**disappointed**  that Dow chose to go forward  with the claim. **We*re 
calling on the federal government to vigorously defend  Quebec*s ban on 
2,4-D.** 
 

Martin Mittelstaedt is The Globe*s Environment Reporter  
----------------------------------------------------------------------------
---------
Obviously, they haven't seen this latest study! 
 
Glyphosate formulations  induce apoptosis and necrosis in human umbilical, 
embryonic, and placental  cells 
_http://www.ncbi.nlm.nih.gov/pubmed/19105591?ordinalpos=1&itool=EntrezSystem
2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocS
um_ 
(http://www.ncbi.nlm.nih.gov/pubmed/19105591?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RV
DocSum)  
Benachour N, Séralini GE. 
 
UniVersity of Caen, Laboratory Estrogens and  Reproduction, UPRES EA 2608, 
Institute of Biology, Caen 14032, France. 
 
We have evaluated the toxicity of four glyphosate (G)-based  herbicides in 
Roundup formulations, from 10(5) times dilutions, on three  different human 
cell types. This dilution level is far below agricultural  recommendations 
and corresponds to low levels of residues in food or feed. The  formulations 
have been compared to G alone and with its main metabolite AMPA or  with one 
known adjuvant of R formulations, POEA. HUVEC primary neonate umbilical  
cord vein cells have been tested with 293 embryonic kidney and JEG3 placental  
cell lines. All R formulations cause total cell death within 24 h, through 
an  inhibition of the mitochondrial succinate dehydrogenase activity, and 
necrosis,  by release of cytosolic adenylate kinase measuring membrane damage. 
They also  induce apoptosis via activation of enzymatic caspases 3/7 
activity. This is  confirmed by characteristic DNA fragmentation, nuclear 
shrinkage (pyknosis), and  nuclear fragmentation (karyorrhexis), which is 
demonstrated by DAPI in apoptotic  round cells. G provokes only apoptosis, and 
HUVEC 
are 100 times more sensitive  overall at this level. The deleterious effects 
are not proportional to G  concentrations but rather depend on the nature of 
the adjuvants. AMPA and POEA  separately and synergistically damage cell 
membranes like R but at different  concentrations. Their mixtures are 
generally even more harmful with G. In  conclusion, the R adjuvants like POEA 
change 
human cell permeability and amplify  toxicity induced already by G, through 
apoptosis and necrosis. The real  threshold of G toxicity must take into 
account the presence of adjuvants but  also G metabolism and time-amplified 
effects or bioaccumulation. This should be  discussed when analyzing the in 
vivo toxic actions of R. This work  clearly confirms that the adjuvants in 
Roundup formulations are not inert.  Moreover, the proprietary mixtures 
available on the market could cause cell  damage and even death around residual 
levels to be expected, especially in food  and feed derived from R 
formulation-treated crops.
 
 (http://www.papercut.biz/emailStripper.htm)  
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