Have you read this (and the linked documents)?
http://www.virtualizationteam.com/virtualization-vmware/vmware-vi3-virtualization-vmware/dont-use-vmware-raw-device-mapping-rdm-for-performance-but.html

--Matt

On Mon, May 16, 2011 at 12:00 PM, Tim Kirby <[email protected]> wrote:
> So, given the following:
>
>  ESXi 4.x servers with 10GigE connectivity to a NAS
>  that supports both NFS and iSCSI
>
> Consider the virtualization of, say, a Linux mysql
> server (previously a server with FC attached storage).
>
> There are various possibilities for the database(s).
> I believe the very last thing one would want to do is
> put the DB in the vmdk, however there are four other
> options:
>
>   ESX NFS mount of space from storage
>   ESX iSCSI mount of space from storage
>   Client OS (Linux) NFS mount of space from storage
>   Client OS (Linux) iSCSI mount of space from storage
>
> There seem to be pros and cons of all and I'm trying
> to determine how many of them are dinosaur-thinking
> based on ancient history and how many are relevant to
> today.
>
> So, I'm tossing this out for a community wisdom poll :)
>
> While I'm at it, I have a sense that the current thought
> is that vmdk over NFS is preferable to vmdk over iSCSI;
> I'll ask for any comments on that while I'm at it.
>
> Thanks for your time.
>
> Tim
> --
> Tim Kirby                   [email protected]
>
>
>
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