Smallpox. Mic drop on anyone anti vax. Also, for Texas cavers it sounds like signing emails is a bigger issue then zika. Just saying.
-gp On May 24, 2016 10:21 PM, "Rafal Kedzierski via Texascavers" < texascavers@texascavers.com> wrote: Malaria is a parasite not a virus, different bird. We actually do pretty good job developing resistence to chickenpox, hence vaccination program wasn't deemed viable until 1990s. And vaccines aren't harmless - no autism significance as of now - but small but real possibility of demyelinating processes. Vaccine is completely effective in 40 percent of kids. Childhood varicella vaccinations are also likely responsible for adult shingles epidemic now - vaccine just isn't as good at long term protection. No need to worry - there are medication and vaccine for shingles now!! And more research is always needed;). No such thing as no risk in investment - or medicine. RK > To: texascavers@texascavers.com > Date: Wed, 25 May 2016 01:01:59 +0000 > Subject: Re: [Texascavers] Zika > From: texascavers@texascavers.com > > Develop resistance in the same way that we’ve done with malaria and chickenpox? > > Thanks goodness for vaccines and anti-malarial drugs…which are still being developed, due to problems with resistance. > > Diana > > ************************************************** > Diana R. Tomchick > Professor > Departments of Biophysics and Biochemistry > University of Texas Southwestern Medical Center > 5323 Harry Hines Blvd. > Rm. ND10.214A > Dallas, TX 75390-8816 > diana.tomch...@utsouthwestern.edu > (214) 645-6383 (phone) > (214) 645-6353 (fax) > > > On May 24, 2016, at 7:37 PM, texascavers@texascavers.com wrote: > > > > Your medical industrial complex is wanting you to write them a 1.9 billion dollar check for initial funding for Zika virus research and prevention. Or about 40 dollars for each of those households paying taxes. Few billion will follow every year from now on until story is forgotten by public 10 years from now. What's a few billions among friends? > > > > But this will likely not change anything. Zika will spread across southern us until it becomes ubiquitous and is population will gain resistence. Then likely 95% of complications will disappear. This will become just like any of hundreds of minimally pathologic viruses, with more to follow. Next year look out for Kiki virus - one that elongates fetal noses and prompts another emergent spending bill;). > > > > Cytomegalovirus and varicella invade brains of fetuses, Zika is nothing special. Dozens of other viruses grow in neuronal cultures - nothing special, except CV padding material. > > > > Messenger doesn't change the message. And it was signed;). > > > > RK > > > > > To: texascavers@texascavers.com > > > Date: Tue, 24 May 2016 22:27:10 +0000 > > > Subject: Re: [Texascavers] Zika > > > From: texascavers@texascavers.com > > > > > > Just because you’ve already procreated doesn’t mean everyone else has, Rafal Kedzierski. > > > > > > It’s ironic that you should be against more research, given your background. > > > > > > Diana > > > > > > ************************************************** > > > Diana R. Tomchick > > > Professor > > > Departments of Biophysics and Biochemistry > > > University of Texas Southwestern Medical Center > > > 5323 Harry Hines Blvd. > > > Rm. ND10.214A > > > Dallas, TX 75390-8816 > > > diana.tomch...@utsouthwestern.edu > > > (214) 645-6383 (phone) > > > (214) 645-6353 (fax) > > > > > > > On May 24, 2016, at 5:22 PM, texascavers@texascavers.com wrote: > > > > > > > > Yes, living is scary and it ends in death, funny how that goes. > > > > > > > > Every new scary story just needs 'mo money' for 'mo research'. For that we just need 'mo taxes'. > > > > > > > > Look, when every potential mother aquites immunity, more than likely maternal fetal infections will cease. Sometimes you don't need no more 'mo'. > > > > > > > > That's coming from a physician and a scientist. > > > > > > > > RK > > > > > > > > > To: texascavers@texascavers.com > > > > > Date: Tue, 24 May 2016 21:43:41 +0000 > > > > > Subject: Re: [Texascavers] Zika > > > > > From: texascavers@texascavers.com > > > > > > > > > > > Try telling a potential parent that Zika is something not to worry about and see how far that argument gets you. > > > > > > > > > > Perhaps we should tell people in Zika infected countries to not get pregnant? > > > > > > > > > > (Dons fireproof suit) ;-) > > > > > > > > > > Stefan Creaser > > > > > Staff Design Engineer; Physical Design Group; ARM > > > > > 5707 Southwest Parkway, Bldg 1, Suite 100, Austin, TX 78735, USA. > > > > > Direct: +1-512-314-1012, Internal: 11012. > > > > > Email: stefan.crea...@arm.com. Skype: stefan_creaser > > > > > > > > > > -----Original Message----- > > > > > From: Texascavers [mailto:texascavers-boun...@texascavers.com] On Behalf Of Diana Tomchick via Texascavers > > > > > Sent: Tuesday, May 24, 2016 4:39 PM > > > > > To: Cave Tex > > > > > Subject: Re: [Texascavers] Zika > > > > > > > > > > > Microcephaly is seen in population in general, only about 1 in 100 mothers infected with Zika are affected. For comparison, about 40k people die in traffic accidents a year in brazil, 40K in US, 200K in India. Malaria kills 1 million people a year. > > > > > > > > > > > > > > > Yes, but not every virus causes problems with neural development in embryonic cell cultures. > > > > > > > > > > "Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth” > > > > > Tang, Hengli et al. > > > > > Cell Stem Cell , Volume 18 , Issue 5 , 587 - 590 > > > > > > > > > > For a freely available description of this research, > > > > > > > > > > http://www.sciencemag.org/news/2016/03/zika-virus-kills-developing-brain-cells > > > > > > > > > > The very last sentence of this description sums up the problem rather well: > > > > > > > > > > "Researchers also still need to figure out how the virus crosses the placenta and infects the fetus directly, something most viruses can’t do.” > > > > > > > > > > If the population of Brazil is 205 million, and roughly half the population is female (~100 million), and of that only 50% is of childbearing age (50 million) and only 5% of that number plans to have a child this year (2.5 million), and 1% of that number has children born with microcephaly, that would be 25,000 children, if all the mothers were infected with Zika virus. > > > > > > > > > > Let that sink in: 25,000 children born with microcephaly. > > > > > > > > > > So let’s assume instead that only 25% of the potential mothers are infected with Zika virus and their babies have microcephaly. That would still mean 6,250 children born with microcephaly. > > > > > > > > > > 6,250 children born with so little neural tissue that they will never live independently, and probably will not live very long lives. > > > > > > > > > > According to the CDC ( http://www.cdc.gov/ncbddd/birthdefects/microcephaly.html), > > > > > > > > > > "Microcephaly is not a common condition. State birth defects tracking systems have estimated that microcephaly ranges from 2 babies per 10,000 live births to about 12 babies per 10,000 live births in the Unites States.” > > > > > > > > > > That would be 0.02 - 0.12 % of live births in the U.S., a far smaller number than 1%. > > > > > > > > > > "Zika virus, named after a forest in Uganda where it was first isolated decades ago, usually causes only mild symptoms in people, including fever and rash. But after the virus started spreading across northeastern Brazil last year, doctors there noticed a striking increase in the number of babies born with microcephaly.” > > > > > > > > > > This is exactly what epidemiologists are supposed to do, alert the medical community to potential new health risks. Not all new viruses and pathogens are as terrifyingly dangerous as Ebola, nor as relatively ho-hum as Lone Star fever. One has a high risk of death and the other can be easily treated with antibiotics. > > > > > > > > > > Try telling a potential parent that Zika is something not to worry about and see how far that argument gets you. > > > > > > > > > > Diana > > > > > > > > > > ************************************************** > > > > > Diana R. Tomchick > > > > > Professor > > > > > Departments of Biophysics and Biochemistry > > > > > University of Texas Southwestern Medical Center > > > > > 5323 Harry Hines Blvd. > > > > > Rm. ND10.214A > > > > > Dallas, TX 75390-8816 > > > > > diana.tomch...@utsouthwestern.edu > > > > > (214) 645-6383 (phone) > > > > > (214) 645-6353 (fax) > > > > > > > > > > > On May 24, 2016, at 3:45 PM, texas cavers tc < texascavers@texascavers.com> wrote: > > > > > > > > > > > > Just to provide a different perspective, only 1 in 5 even know have Zika related illness when they are exposed. It's not 'spiraling out of control' - it's new to North America, yes. It's likely one of many illnesses that go through populations and become part of the infectious tapestry that we all live in. Is anyone reading alarmist articles about Heartland virus or Lone Star fever? > > > > > > > > > > > > Guillan-Barre syndrome is secondary to number of viruses, it's nothing specific to Zika. > > > > > > > > > > > > Microcephaly is seen in population in general, only about 1 in 100 mothers infected with Zika are affected. For comparison, about 40k people die in traffic accidents a year in brazil, 40K in US, 200K in India. Malaria kills 1 million people a year. > > > > > > > > > > > > RK > > > > > > > > > > > > See http://www.medicalnewstoday.com/articles/305163.php > > > > > > Symptoms of Zika virus > > > > > > > > > > > > Signs and symptoms of Zika virus are vague and can last for up to a week. Diagnosis of the virus is typically confirmed with a blood test.1 > > > > > > Symptoms of Zika virus include:1,2 > > > > > > • Fever > > > > > > • Rash > > > > > > • Joint pain > > > > > > • Conjunctivitis (red eyes) > > > > > > • Muscle pain > > > > > > • Headache > > > > > > • Pain behind the eyes > > > > > > • Vomiting. > > > > > > According to the Pan American Health Organization (PAHO), only 1 in 4 people infected with Zika virus develop symptoms.5 In contrast, the CDC state the figure is 1 in 5. > > > > > > In the past, there have also been reports of patients developing Guillain-Barré syndrome following a Zika virus infection. Guillain-Barré syndrome is a rare but serious autoimmune disorder that affects the central nervous system.6 > > > > > > Infection with the Zika virus is rarely severe enough to warrant hospitalization, and it is rarer still for an individual to die as a result.6 > > > > > > > > > > > > _______________________________________________ > > > > > > Texascavers mailing list | http://texascavers.com > > > > > > Texascavers@texascavers.com | Archives: http://www.mail-archive.com/texascavers@texascavers.com/ > > > > > > http://lists.texascavers.com/listinfo/texascavers > > > > > > > > > > > > > > > ________________________________ > > > > > > > > > > UT Southwestern > > > > > > > > > > > > > > > Medical Center > > > > > > > > > > > > > > > > > > > > The future of medicine, today. > > > > > > > > > > > > > > > _______________________________________________ > > > > > Texascavers mailing list | http://texascavers.com > > > > > Texascavers@texascavers.com | Archives: http://www.mail-archive.com/texascavers@texascavers.com/ > > > > > http://lists.texascavers.com/listinfo/texascavers > > > > > IMPORTANT NOTICE: The contents of this email and any attachments are confidential and may also be privileged. If you are not the intended recipient, please notify the sender immediately and do not disclose the contents to any other person, use it for any purpose, or store or copy the information in any medium. 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