Michelle, 
Below is an abstract that I found on PubMed (I searched for sensory specific satiety). 
In that study they used PET scans to show changes in the areas of human brains that 
were activated by chocolate when it was perceived as pleasant and later when the 
participants ate chocolate after having reached satiety. The finding suggests that 
once we have reached satiety for a particular taste that the same stimulus activates 
different areas of cortex. These authors suggest that these later areas are associated 
with punishment.

My best
Dennis

Small DM, Zatorre RJ, Dagher A, Evans AC, & Jones-Gotman M. (2001). Changes in brain 
activity related to eating chocolate: from pleasure to aversion. Brain, 124, 1720-33 

We performed successive H(2)(15)O-PET scans on volunteers as they ate chocolate to 
beyond satiety. Thus, the sensory stimulus and act (eating) were held constant while 
the reward value of the chocolate and motivation of the subject to eat were 
manipulated by feeding. Non-specific effects of satiety (such as feelings of fullness 
and autonomic changes) were also present and probably contributed to the modulation of 
brain activity. After eating each piece of chocolate, subjects gave ratings of how 
pleasant/unpleasant the chocolate was and of how much they did or did not want another 
piece of chocolate. Regional cerebral blood flow was then regressed against subjects' 
ratings. Different groups of structures were recruited selectively depending on 
whether subjects were eating chocolate when they were highly motivated to eat and 
rated the chocolate as very pleasant [subcallosal region, caudomedial orbitofrontal 
cortex (OFC), insula/operculum, striatum and midbrain] or whether they ate chocolate 
despite being satiated (parahippocampal gyrus, caudolateral OFC and prefrontal 
regions). As predicted, modulation was observed in cortical chemosensory areas, 
including the insula and caudomedial and caudolateral OFC, suggesting that the reward 
value of food is represented here. Of particular interest, the medial and lateral 
caudal OFC showed opposite patterns of activity. This pattern of activity indicates 
that there may be a functional segregation of the neural representation of reward and 
punishment within this region. The only brain region that was active during both 
positive and negative compared with neutral conditions was the posterior cingulate 
cortex. Therefore, these results support the hypothesis that there are two separate 
motivational systems: one orchestrating approach and another avoidance behaviours.


-----Original Message-----
From: Michelle Miller [mailto:[EMAIL PROTECTED]]
Sent: Tuesday, October 08, 2002 5:56 PM
To: Teaching in the Psychological Sciences
Subject: A matter of taste


Hello - Here is a question about gustation -- What is the mechanism that
causes us to view a food as attractive or unattractive depending on how
recently we've been exposed to it?  As omnivores, we're clearly
powerfully driven to eat a variety of foods, and when we are
over-exposed to even a very tasty food, we become averse to it.  (Like
how Nora Ephron , in her journalism days, once wrote about covering the
Pillsbury Bake-Off - after a couple of hours in an environment full of
"snicky snacky crispy crunchy" foods, she said she would have given
anything for a steak.)  I'm assuming that this is a large part of why
restrictive diets work for some people - all the bacon and eggs you can
eat sounds good for a meal or two, but soon, you'd rather just not eat
at all.

Thanks, I'm just curious.

-- Dr. Michelle Miller
Assistant Professor
Department of Psychology
Northern Arizona University
Flagstaff, AZ 86001-5106
[EMAIL PROTECTED]
 http://jan.ucc.nau.edu/~mdm29/

NAU Department of Psychology:
 http://www.nau.edu/~psych/naupsy.html


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