Hi Stephen et al.: By "transaction," I mean the notion that both genes and environment both play important roles in the development of a given individual.  I suspect we'll all agree with this relatively uncontroversial assertion.  But this differs markedly, although is frequently confused with, the more specific conception of gene (or more precisely, genotype) by environment interaction, which as you note, imply that the effects of genes and environment across individuals (not within a given individual) are multiplicative rather than additive, that is, that the effects of genes differ depending on the levels of one or more environmental variables, and vice-versa for the effects of the environment.  Probably as good a source as any for a general review of this topic (and many others) is Plomin, DeFries, McClearn, and Rutter's (2000) text, Behavior Genetics (Freeman).  ...Scott

Stephen Black wrote:
On 6 Dec 2004, Scott Lilienfeld wrote:

  
My reading of the human literature is that the research evidence for 
gene-environment interaction (in the sense of a statistical interaction, 
not gene-environment "transaction," which I suspect most of us now 
accept as a truism) is still fairly sparse.
    
<snip>

  
In other psychopathological domains (e.g., schizophrenia,  
    
alcoholism), 
  
there is strong evidence for genetic and environmental main effects, but 
still relatively little for gene-environment interactions
    

Scott:

This is interesting, but I'm not sure I understand. Could you 
elaborate on what you have in mind in referring to the "gene-
environment "transaction" " which we probably all accept?

Also, in the case of schizophrenia, are you suggesting that in some 
cases the cause may be genetic and in other cases the cause may be 
environmental, but that evidence is weak that the cause may be a 
particular genotype in the presence of a particular stressor?

Have any sources to direct us to to read up on this?

Stephen
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