At 8:28 PM -0600 12/9/06, Shearon, Tim wrote:
Paul Annette and others:

I'm not disagreeing with Paul's skepticism either but effects only 12 - 15 % over placebo

The problem is that it is not clear that even the 12-15% is a real difference in the sense that itis due to a specific drug effect.
Placebos are not perfect.
In particular the side effects of drugs are often discriminable from placebos (a true placebo would have the same side effects as the drug to which it was being compared) so it is possible that subjects in studies may be aware of whether they are in the drug or placebo condition, possibly accounting for the (small) difference between placebo and drug groups. See <http://scholar.google.com/url?sa=U&q=http://www.journals.apa.org/pt/prevention/volume1/pre0010002a.html>

are quite meaningful to those 12 - 15 %. :) One would like to think, however, that the billions of dollars spent is somehow related to huge effects which Paul rightly points out are largely absent. BTW- drug company claims to effects are closer to 85 - 92% with placebos at 30 - 50%. Just don't look too closely at how they arrive at these numbers as they do not reflect appropriate skepticism, as Paul points out.


--
The best argument against intelligent design is that people believe in it.

* PAUL K. BRANDON                     [EMAIL PROTECTED] *
* Psychology Department                        507-389-6217 *
* 23 Armstrong Hall     Minnesota State University, Mankato *
*           http://krypton.mnsu.edu/%7Epkbrando/            *

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