On 4 Mar 2009 at 0:10, David Epstein wrote:
 
> HOWEVER, I've never seen any reference to a forced-swimming test in
> which rodents were permitted to drown 

Of course there is the classic (1957) study of  the psychologist and 
psychobiologist Curt Richter showing that dewhiskered wild rats 
introduced into water-filled cylinders would die, often within a few 
minutes. He attributed the cause of death not to drowning from 
exhaustion, but to the stress induced by cutting off the whiskers.

However, his study started with measuring the time to drowning from 
exhaustion in intact rats. See his Figure 2, captioned "Curve showing 
average survival time (end point drowning) unconditioned tame 
domesticated Norway rats with relation to water temperature. Averages for 
7 rats at each point" [ they lasted from 10 minutes to 60 hrs].

So it was done, just not in psychopharmacology, apparently.

http://www.psychosomaticmedicine.org/cgi/reprint/19/3/191.pdf


Richter, C.P. (1957). On the phenomenon of sudden death in animals and 
man. Psychosomatic Medicine, 19, 191-8.


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