I am not a fan of self-dosing with vitamins. From what I've seen, except 
for people with demonstrated deficiencies, most studies find little 
positive effect from vitamin supplementation. In fact, the trend seems to 
be to finding that they are harmful.

But I make an exception for vitamin D. There is evidence that vitamin D 
deficiency is not uncommon, particularly in darker-skinned people and 
particularly in Northern latitudes (can you say Canada?). In recent 
years, hiding from the sun for fear of  getting skin cancer seems to have 
contributed to this state of affairs. 

There is also evidence, albeit mostly correlational, that vitamin D 
supplementation helps prevent disease. One of the most intriguing bits of 
evidence is a relation that has been demonstrated for some diseases, most 
recently type 1 diabetes, to latitude (e.g see 
http://www.physorg.com/news131866757.html ). That is, the incidence of 
diabetes is highest in high northern (e.g. Canada) and southern (e.g. New 
Zealand) latitudes, and lowest around the equator. In high latitudes, sun 
exposure is least, and therefore so is vitamin D synthesis in the skin.

 Of course, other explanations are possible, including, as one news 
summary reports,  "Low levels of vitamin D in patients with autoimmune 
disease may be result, not cause, of the disease" (Science Daily, April 
16/09, http://www.sciencedaily.com/releases/2009/04/090408164415.htm ). 
So the inverse link between vitamin D and disease is not a slam-dunk. 

This brings me to autism. A Scientific American review yesterday (April 
24) discusses the hypothesis that vitamin D deficiency may be a cause of 
autism ( http://www.sciam.com/article.cfm?id=vitamin-d-and-autism). 
The starting point is a curious phenomenon in which Somali (a low 
latitude location) immigrants to Sweden and Minnesota (both high latitude 
locations) appear to have an incidence of autism three to four times 
higher than others. The speculative hypothesis is that this is because 
the Somalis, especially Somali women, get far less sun exposure in their 
new Northern homes. This could be significant during pregnancy, leading 
to vitamin D deficiency and predisposition to autism. 

If so, then vitamin D supplementation during pregnancy may reduce the 
incidence of autism. The Sci Amer article notes that a pilot study is 
underway to look at this.  I would also like to know whether, as 
demonstrated for diabetes,  autism (in general, not just for Somalis) 
increases with increasing latitude.  As far as I know, no one has 
reported such a relationship. 

Stephen
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Stephen L. Black, Ph.D.          
Professor of Psychology, Emeritus   
Bishop's University      e-mail:  [email protected]
2600 College St.
Sherbrooke QC  J1M 1Z7
Canada

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