I have several autoimmune diseases, but my M.D. tested my vitamin D levels  
because of calcium supplementation, since I have osteopenia.  She said that 
 calcium is not absorbed well without adequate Vitamin D.  Since one of my  
problems is vitiligo, I wear sunscreen all the time.  Turns out my Vitamin  
D levels were super low and I have been on megadoses at various intervals ( 
from  several times a week to weekly, etc.) for over a year. It was only 
recently  that my levels are really good.  My husband had his levels checked 
and he  was also deficient, although his levels came up before mine. It is 
definitely  worth checking out Vitamin D , even if only to prevent 
osteoporosis, but the  research you cite has many other implications.  Thanks 
for the 
info.
 
Riki
 
 
In a message dated 4/25/2009 9:43:29 P.M. Eastern Daylight Time,  
[email protected] writes:

I am not  a fan of self-dosing with vitamins. From what I've seen, except 
for people  with demonstrated deficiencies, most studies find little 
positive effect  from vitamin supplementation. In fact, the trend seems to 
be to finding  that they are harmful.

But I make an exception for vitamin D. There is  evidence that vitamin D 
deficiency is not uncommon, particularly in  darker-skinned people and 
particularly in Northern latitudes (can you say  Canada?). In recent 
years, hiding from the sun for fear of  getting  skin cancer seems to have 
contributed to this state of affairs.  

There is also evidence, albeit mostly correlational, that vitamin D  
supplementation helps prevent disease. One of the most intriguing bits of  
evidence is a relation that has been demonstrated for some diseases, most  
recently type 1 diabetes, to latitude (e.g see  
http://www.physorg.com/news131866757.html ). That is, the incidence of  
diabetes is highest in high northern (e.g. Canada) and southern (e.g. New  
Zealand) latitudes, and lowest around the equator. In high latitudes, sun  
exposure is least, and therefore so is vitamin D synthesis in the  skin.

Of course, other explanations are possible, including, as one  news 
summary reports,  "Low levels of vitamin D in patients with  autoimmune 
disease may be result, not cause, of the disease" (Science  Daily, April 
16/09,  http://www.sciencedaily.com/releases/2009/04/090408164415.htm ). 
So the  inverse link between vitamin D and disease is not a slam-dunk. 

This  brings me to autism. A Scientific American review yesterday (April 
24)  discusses the hypothesis that vitamin D deficiency may be a cause of  
autism ( http://www.sciam.com/article.cfm?id=vitamin-d-and-autism).  
The starting point is a curious phenomenon in which Somali (a low  
latitude location) immigrants to Sweden and Minnesota (both high latitude  
locations) appear to have an incidence of autism three to four times  
higher than others. The speculative hypothesis is that this is because  
the Somalis, especially Somali women, get far less sun exposure in their  
new Northern homes. This could be significant during pregnancy, leading  
to vitamin D deficiency and predisposition to autism. 

If so, then  vitamin D supplementation during pregnancy may reduce the 
incidence of  autism. The Sci Amer article notes that a pilot study is 
underway to look  at this.  I would also like to know whether, as 
demonstrated for  diabetes,  autism (in general, not just for Somalis) 
increases with  increasing latitude.  As far as I know, no one has 
reported such a  relationship.  

Stephen
-----------------------------------------------------------------
Stephen  L. Black, Ph.D.          
Professor of Psychology,  Emeritus   
Bishop's University      e-mail:   [email protected]
2600 College St.
Sherbrooke QC  J1M  1Z7
Canada

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